Charge sensing by organic charge-modulated field effect transistors: application to the detection of bio-related effects

Demelas, Monia; Lai, Stefano; Spanu, Andrea; Martinoia, Sergio; Cosseddu, Piero; Barbaro, Massimo; Bonfiglio, Annalisa

doi:10.1039/c3tb20237b

Cited by 37 publications

(35 citation statements)

References 22 publications

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“…These structures include electrochemical transistors, [21] the electrolyte-gated TFTs, [7a,22] the organic charge-modulated FETs, [23] as well as structures involving back gates [24] or double gates. [25] Thed evices listed above are usually classified into two main categories:t ransistors that involve an ionic conductor and those that use an insulator as the dielectric medium.…”

Section: Introduction 12563mentioning

confidence: 99%

Printable Bioelectronics To Investigate Functional Biological Interfaces

et al. 2015

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Thin-film transistors can be used as high-performance bioelectronic devices to accomplish tasks such as sensing or controlling the release of biological species as well as transducing the electrical activity of cells or even organs, such as the brain. Organic, graphene, or zinc oxide are used as convenient printable semiconducting layers and can lead to high-performance low-cost bioelectronic sensing devices that are potentially very useful for point-of-care applications. Among others, electrolyte-gated transistors are of interest as they can be operated as capacitance-modulated devices, because of the high capacitance of their charge double layers. Specifically, it is the capacitance of the biolayer, being lowest in a series of capacitors, which controls the output current of the device. Such an occurrence allows for extremely high sensitivity towards very weak interactions. All the aspects governing these processes are reviewed here.

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Section: Introduction 12563mentioning

confidence: 99%

Printable Bioelectronics To Investigate Functional Biological Interfaces

et al. 2015

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“…The OSC is thermally sublimated then is condensed on the cold substrate to form a film, the thickness of which being controlled by the deposition time and the temperature [51,52].…”

Section: Vacuum Thermal Evaporationmentioning

confidence: 99%

Electrolytic Gated Organic Field-Effect Transistors for Application in Biosensors—A Review

2016

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Electrolyte-gated organic field-effect transistors have emerged in the field of biosensors over the last five years, due to their attractive simplicity and high sensitivity to interfacial changes, both on the gate/electrolyte and semiconductor/electrolyte interfaces, where a target-specific bioreceptor can be immobilized. This article reviews the recent literature concerning biosensing with such transistors, gives clues to understanding the basic principles under which electrolyte-gated organic field-effect transistors work, and details the transduction mechanisms that were investigated to convert a receptor/target association into a change in drain current.

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“…Employing an ultrathin, hybrid organic/inorganic dielectric, the authors obtained operating voltages in the range of 1 V (Cosseddu, Lai, Barbaro, & Bonfiglio, 2012;Demelas et al, 2013). This peculiar characteristic improved not only the portability of the device, but also the reliability of measurements in aqueous media with respect to implementation of high voltage.…”

Section: Deoxyribonucleic Acid Detectionmentioning

confidence: 96%