“…On the other hand, the classification proposed by Kitagawa et al was not just a single categorizing score, as shown in the systematic review, but encompassed 2 different approaches. The first step assessed the size of the guttae, similar to the approach of Laing et al 2,8 Subsequently, the density of the guttae was subjectively categorized using the criteria outlined in Table 5. 1,2 Shearer et al 9 classified FECD cases according to the central region cell…”