The vertical growth of multi storied buildings has become requisite considering limitations on housing area and upsurge in population growth. Cities with population density >10000 person/Km2may go for high rise buildings. Multiple cases of foundation failure have been observed around the globe due to incompetent soil, weak foundation, poor building materials, faulty workmanship, excess superimposed loading, want of geotechnical investigations, and failure analysis. The analysis and design of multistoried buildings [minimum G +3]is of demand in urban and economically sound areas. The STAAD. Pro is an efficient tool adhering to IS specifications for design of structures by limit state design to avoid erroneous computations, cumbersome and time consuming processes of manual calculation in India. The software is user interface to visualize, analyze and design structures by radical finite element technique and has dynamic analysis abilities. The present work is a 3-D RCC frame having 4 bays x5m along x-direction and 3 bays x5m in z- direction were taken where each floor has 299 beams and 40umns at different elevations in each floor subjected to dead, live , wind and seismic loads as per Indian beneath different load arrangements, considering structural safety under minimum requirements. The perception levels against vibrations and different foundations against failure (especially pile foundation) is stressed for a safe, comfortable multi storied building in Indian soil.