Chemical analyses of the essential oils from leaves of<i>Mikania glauca</i>Mart. ex Baker

Guimarães, Luiz Gustavo de Lima; Cardoso, María das Graças; Silva, Lucilene F.; Gomes, Marcos de Souza; Andrade, Milene Aparecida; Souza, Josefina Aparecida de; Miranda, Cíntia Alvarenga Santos Fraga de; Andrade, Juliana de; Machado, Samísia Maria Fernandes; Figueiredo, A. Cristina; Barroso, José G.; Mansanares, Mariana Esteves; Nelson, David Lee

doi:10.1080/10412905.2012.742789

Cited by 5 publications

(3 citation statements)

References 12 publications

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“…In Mikania's essential oils composition, germacrene D, bicyclogermacrene, caryophyllene oxide, and spathulenol have been reported as the major compounds (Limberger et al 2001;Ferreira and De Oliveira 2010;Guimarães et al 2012). These components are related to some biological activities, such as intense antimicrobial activity (Betoni et al 2006;Duarte et al 2007;Matawali et al 2016) and vigorous activity against Candida albicans (Duarte et al 2005).…”

Section: Chromatographic Analysismentioning

confidence: 99%

“…Besides, Gasparetto et al (2012b) quoted germacrene D, bicyclogermacrene, caryophyllene oxide, and spathulenol, α-humulene, germacrene B as major constituents involved in Mikania's biological effects. Guimarães et al (2012) studied Mikania glauca's essential oil from two seasons, winter and spring. Their chromatography analysis demonstrated the predominance of monoterpene hydrocarbons in the essential oil and the influence of season on components concentrations.…”

Section: Chromatographic Analysismentioning

confidence: 99%

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Biomass production, essential oil’s yield and composition of three genotypes of Mikania laevigata Sch. Bip. ex Baker

et al. 2021

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Mikania laevigata leaves are used worldwide as herbal medicines. Our study investigates the production differences among three different genotypes of this herb: the genotypes' influence on the essential oil yield, chemical composition, and the plant tissues involved in the secretion of the chemical compounds produced by the leaves. The study performed the analysis during the summer and winter seasons. Plants were grown under an organic cultivation system in Oratórios, Minas Gerais, Brazil. Essential oils were extracted by hydrodistillation and analyzed by gas chromatography/mass spectrometer. The analysis highlighted substantial genetic variability among the genotypes. The genotype CENARGEN showed higher biomass production, oil yield, and a high concentration of major constituents detected by chromatographic analysis in essential oils, such as germacrene D and caryophyllene oxide. The season affected the chemical composition of the essential oils. Germacrene D and bicyclogermacrene were the major constituents in the winter-essential-oils; spatulenol and caryophyllene oxide were the major constituents in the summer-essential-oils.

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Section: Chromatographic Analysismentioning

confidence: 99%

Section: Chromatographic Analysismentioning

confidence: 99%

Biomass production, essential oil’s yield and composition of three genotypes of Mikania laevigata Sch. Bip. ex Baker

et al. 2021

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“…A vast majority of plants in this Family are herbaceous, while trees and shrubs are comparatively rare" [24]. "Asteraceae species have been widely used in folk medicine for several therapeutic purposes" [25], and "are very common in different regions of Brazil, mainly in the Cerrado (savanna) biome, where this family is well represented by the approximately 250 genera and more than 2000 species" [26].…”

Section: Ethnobotany and Ethno-medicine Observationsmentioning

confidence: 99%

Genus Vernonia (Asteraceae): A Promising Source of Antitumor Agents with Pharmacological Potentials

Gonzatto

Araújo²,

Albuquerque³

2022

AIR

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Antitumor research leads to the development of new molecules that act specifically in tumor cells by blocking or inhibiting their molecular targets. New therapeutic approaches for the screening of bioactive compounds present in medicinal plants have received increasing attention due to their chemopreventive and chemotherapeutic properties. In ethnomedicine, plants of the genus Vernonia (Asteraceae) are widely used and some have shown several and interesting biological activities, including anticancer. This present study aimed to document experimental evidence supporting the claimed ethnomedical uses of Vernonia species for the treatment of various types of cancer and also to confirm the anticancer potential of these plants. The compounds isolated from aqueous and alcoholic extracts, as well as fractions from different parts of Vernonia plants have acted as potential anticancer agents that inhibited the proliferation of various types of human cancer cell lines, including cervical cancer cells, melanoma cells, promyelocytic leucemia cells, breast adenocarcinoma cells, ovarian cancer, liver cancer cell, and human lung cancer cells. Studies have correlated the antitumor activity of Vernonia plants by inducing apoptosis and modulating mitochondrial signaling pathways controlled by NF-κB, Bcl-2 and p53, as well as inducing DNA damage and arresting the cell cycle at the S-phase checkpoint by oxidative stress. In conclusion, Vernonia species act as a promising source for drug development. However, further studies are needed to explore the exact mechanism of action, pharmacokinetics, chronic toxicological studies, safe dose consumption, and possible interactions with other herbs.

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In vitro activity evaluation of seven Brazilian Asteraceae against cancer cells and Leishmania amazonensis

Silva¹,

Nascimento²,

Rodrigues

et al. 2019

South African Journal of Botany

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Chemical analyses of the essential oils from leaves ofMikania glaucaMart. ex Baker

Cited by 5 publications

References 12 publications

Biomass production, essential oil’s yield and composition of three genotypes of Mikania laevigata Sch. Bip. ex Baker

Biomass production, essential oil’s yield and composition of three genotypes of Mikania laevigata Sch. Bip. ex Baker

Genus Vernonia (Asteraceae): A Promising Source of Antitumor Agents with Pharmacological Potentials

In vitro activity evaluation of seven Brazilian Asteraceae against cancer cells and Leishmania amazonensis

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