Chemical analysis and antioxidant activity in vitro of a β-d-glucan isolated from Dictyophora indusiata

Mechanism of the immunostimulatory activity by a polysaccharide from Dictyophora indusiata

“…The average molecular weight was estimated at 650 kDa through gel permeation chromatography. In our previous study, gas chromatography-mass spectrometry and infrared spectrum analysis indicated that DIP was a β-D-glucan [10]. The extraction procedure of DIP from D. indusiata and its physiochemical properties was shown in Fig.…”

“…DIP was isolated and purified as described previously with slight modification [10]. In brief, D. indusiata powder was extracted with distilled water at 90 o C and the mixture was then centrifuged to isolate the supernatant.…”

“…indusiata also exhibits excellent antioxidant [10], antitumor and immunostimulatory 4 activities [11,2]. However, as a widely used immunomodulatory nutrient ， the molecular mechanism of the polysaccharide from D. indusiata has remained largely elusive.…”

Beta-glucans from edible and medicinal mushrooms: Characteristics, physicochemical and biological activities

“…A growing body of science indicates that b-glucans promote health in a number of important ways, such as immuno-modulatory, antitumor, antiviral, (Borchers et al, 2004;Moradali et al, 2007), cardiovascular (Wasser and Weis, 1999), liver protective, antiinflammatory, (Lindequist et al, 2005), radioprotective (Pillai and Devi, 2013), antidiabetic (Kim et al, 2005), antioxidant (Deng et al, 2012), antibacterial (Suay et al, 2000;Ishikawa et al, 2001;Shittu et al, 2005;Beattie et al, 2010), and antiobesity activities . Antitumour activity (Kidd, 2000;Zhang et al, 2007;Deng et al, 2012;Ren et al, 2012) and immune-modulating activity (Wasser, 2002) of mushroom b-glucan have been documented in the previous reviews. Thus, the current review focuses on the antibacterial activity, antiviral activity and radioprotective effect of mushroom b-glucan.…”

Immunomodulation of myeloid-derived suppressor cells by particulate b-glucan in cancer.

“…A large variety of β-glucans have been reported in the cell walls of different species of mushrooms, yeast, oat, barley, seaweeds, algae and bacteria (53)(54)(55)(56)(57)(58)(59)(60). The polymer chains of β-glucans of different sources vary in length, glycosidic linkage configuration, the number and type of branching, the 3-dimensional conformation, and the solubility in water and alkali solutions.…”