Three new bisabolocurcumin ethers, named demethoxybisabolocurcumin ether (1), bisabolocurcumin ether (2), and didemethoxybisabolocurcumin ether (3), along with two known compounds, 4 and 5, were isolated from the AcOEt extract of the rhizomes of Curcuma longa L. Their structures were established by the analysis of NMR and MS data. The new compounds 1 -3, which possess a new 1,7-diarylheptanoid skeleton linked with a bisabolone-type sesquiterpene substructure by a CÀO bond, were found for the first time in a natural source. , and hypoglycemic properties [10]. Up to now, from C. longa, curcuminoids, sesquiterpenoids, and their derivatives were reported as components [11]. In our phytochemical investigation, three new bisabolocurcumin ethers, compounds 1 -3, were isolated from the title plant. In their structures, a bisabolone-type sesquiterpene substructure is combined with a curcuminoid moiety, connected via a CÀO bond. Two known compounds, (1E,4E)-1,5-bis(4-hydroxyphenyl)penta-1,4-dien-3-one (4) [12] and (1E,4E,6E)-1,7-bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one (5) [13], were also isolated.In this article, the isolation and structure determination of the three new compounds are described.