Chemical and Phytochemical Composition of Ashwagandha (Withania somnifera L.) Roots

Gulati, Susheel; Madan, V. K.; Singh, Sushila; Singh, Isha; Dusyant,

doi:10.14233/ajchem.2017.20536

Cited by 13 publications

(11 citation statements)

References 5 publications

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“…The dose used in the present experimental study was calculated on the basis of in vitro antibacterial effect of WSR extract on E. coli ( Kumari and Gupta, 2015 ). Results of other workers revealed that total alkaloids content of WSR collected from the same source as that of present study varied between 0.26 and 0.31%, and tannins content varied between 0.66 and 0.84 mg/g ( Gulati et al., 2017 ).…”

Section: Methodssupporting

confidence: 65%

Ameliorating effect of Withania somnifera root extract in Escherichia coli–infected broilers

et al. 2020

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The present study was undertaken to investigate the effect of aqueous Withania somnifera root ( WSR ) extract in broiler chicks experimentally infected with Escherichia coli O78 @ 10 7 CFU/0.5 ml intraperitoneally. Clinical signs and mortality due to colibacillosis observed in infected chicks were mild and lasted for short duration in WSR extract supplemented group as compared with the nonsupplemented group. A significant increase in serum alanine transaminase, aspartate transaminase, lactate dehydrogenase, and creatine phosphokinase activities and a decrease in total protein and albumin concentrations were observed in the infected groups, though these changes were of lower magnitude in WSR extract supplemented group. A significantly higher activity of oxidative blood parameters such as superoxide dismutase, catalase, glutathione reductase, and glutathione-S-transferase enzymes were noticed in WSR extract supplemented group. The WSR extract supplemented group revealed significantly higher E. coli– specific antibody titer and enhanced lymphocyte proliferation response as compared with the nonsupplemented group. The gross and histopathological lesions of colibacillosis were mild in the WSR extract–supplemented infected group as compared with the nonsupplemented infected group. Withania somnifera root extract supplementation produced 31.48 and 34.38% protection in the gross and histopathological lesions in E. coli infected chicks, respectively. It is concluded that supplementation of 20% WSR extract @ 20 ml/L of water caused a reduction in the severity, mortality, and recovery period of E. coli infection and enhanced the humoral and cellular immune responses suggesting its protective effect on limiting the pathology of E. coli infection in broiler chickens.

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Section: Methodssupporting

confidence: 65%

Ameliorating effect of Withania somnifera root extract in Escherichia coli–infected broilers

et al. 2020

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“…Estimation of total sugars content: Total sugars content was determined by phenol sulphuric acid method [8] using glucose as standard. Detailed method is discussed in previously published paper [9]. The total sugars content present in various extracts was calculated and results were expressed as milligrams per gram (mg/g).…”

Section: Methodsmentioning

confidence: 99%

Effect of Various Extraction Techniques and Solvents on Extract Yield and Sugars Content of Clove (Syzygium aromaticum L.)

Singh¹,

Madan²,

Jangra³

et al. 2018

Asian J. Chem.

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“…For example, it blocks NF-kB transcription, which increases cytokines and other growth-promoting factors during inflammation, inhibits JAK/STAT signaling, which blocks anti-apoptotic, and proteasome-mediated degradation complex inhibition, which blocks apoptotic cell death (Wadhwa et al, 2017a ). Because the plant has several active constituents, it is being cultivated for various pharmaceutical uses to increase biomass and produce high-quality products (Gulati and Singh, 2017 ). Salmonella typhi, Escherichia coli, Pseudomonas aeruginosa , and others have been shown to be susceptible to the leaf extract.…”

Section: Medicinal Plantsmentioning

confidence: 99%

Antiviral perspectives of economically important Indian medicinal plants and spices

Pebam

Sankaranarayanan

Thanekar

et al. 2022

Proc.Indian Natl. Sci. Acad.

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Human respiratory diseases caused by viral infections leads to morbidity. Among infectious diseases, viral infections associated with the respiratory tract remain the primary reason for global deaths due to their transmissibility. Since immemorial, traditional Indian medicinal plants, their extracts, and several phytochemicals can treat various diseases. Sources for this review paper are data derived from a peer-reviewed journal that emphasizes the economic importance of medicinal plants. Several plant-based medicines have been reported to be effective against multiple viral infections, including the Human Adenovirus, Enterovirus, Influenza virus, Hepatitis virus, etc. This review emphasizes use of the Indian medicinal plants like as Withania somnifera (Ashwagandha, Winter Cherry), Moringa oleifera (Drumstick), Ocimum tenuiflorum (Tulsi), Azadirachta indica (Neem), Curcuma longa (Turmeric), Terminalia chebula (Chebulic Myrobalan), Punica granatum (Pomegranate) and the Indian household spices (ginger, garlic and black pepper). It further describes their secondary phytoconstituents extraction procedure, mode of action and the potential application to improve clinical outcomes of neutraceuticals against various viral infections.

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Chemical and Phytochemical Composition of Ashwagandha (Withania somnifera L.) Roots

Cited by 13 publications

References 5 publications

Ameliorating effect of Withania somnifera root extract in Escherichia coli–infected broilers

Ameliorating effect of Withania somnifera root extract in Escherichia coli–infected broilers

Effect of Various Extraction Techniques and Solvents on Extract Yield and Sugars Content of Clove (Syzygium aromaticum L.)

Antiviral perspectives of economically important Indian medicinal plants and spices

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