The work presents data treatment methods aimed at eliminating the noise in the strain sensor data induced by vibrations of the helicopter blade in flight conditions. The methods can be applied in order to enhance the metrological performance of the helicopter weight estimation system based on the deformation measurement of the main rotor blades. The experimental setup included a composite plate fixed to the vibrating stand on the one end, with six fiber-optic strain sensors attached to its surface. In this work, the procedure of the optimal linear smoothing (POLS) and 3D-invariant methods were used to obtain monotone calibration curves for each detector, thereby making it possible to distinguish the increase of load applied to the free end of the plate with an increment of 10 g. The second method associated with 3D invariants took into account 13 quantitative parameters defined as the combination of different moments and their intercorrelations up to the fourth-order inclusive. These 13 parameters allowed the calculation of the 3D surface that can serve as a specific fingerprint, differentiating one set of initial data from another one. The combination of the two data treatment methods used in this work can be applied successfully in a wide variety of applications.