Chemical Burn Caused by Topical Vinegar Application in a Newborn Infant

Korkmaz, Ayşe; Şahiner, Ümit Murat; Yurdakök, Murat

doi:10.1046/j.1525-1470.2000.01707.x

Cited by 24 publications

(6 citation statements)

References 15 publications

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“…case reports and, to a lesser degree, case series [29,30,31,32,33,34,35,36,37,38,39,40,41]. case reports and, to a lesser degree, case series [29,30,31,32,33,34,35,36,37,38,39,40,41].…”

Section: Resultsmentioning

confidence: 99%

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Serious adverse effects of unconventional therapies for children and adolescents: a systematic review of recent evidence

Ernst¹

2003

Eur J Pediatr

141

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Unconventional therapies have become popular in paediatric and adolescent populations. It is therefore important to define their risks. The aim of this systematic review was to summarise the recent evidence. Computerised literature searches were carried out in five databases to identify all recent reports of adverse events associated with unconventional therapies in children. The reports were summarised in narrative and tabular form. The results show that numerous case reports and several case series have been published since 1990. Investigations of a more systematic nature are, however, rare. Most of the adverse events were associated with herbal medications. Inadequately regulated herbal medicines may contain toxic plant material, be contaminated with heavy metals, or be adulterated with synthetic drugs. The adverse events included bradycardia, brain damage, cardiogenic shock, diabetic coma, encephalopathy, heart rupture, intravascular haemolysis, liver failure, respiratory failure, toxic hepatitis and death. A high degree of uncertainty regarding a causal relationship between therapy and adverse event was frequently noted. The size of the problem and its importance relative to the well-documented risks of conventional treatments are presently unknown. Several unconventional therapies may constitute a risk to the health of children and adolescents. At present, it is impossible to provide reliable incidence figures. It seems important to be vigilant and investigate this area more systematically.

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“…case reports and, to a lesser degree, case series [29,30,31,32,33,34,35,36,37,38,39,40,41]. case reports and, to a lesser degree, case series [29,30,31,32,33,34,35,36,37,38,39,40,41].…”

Section: Resultsmentioning

confidence: 99%

“…It was used topically for a Turkish neonate hospitalised for suspected sepsis [38]. It was used topically for a Turkish neonate hospitalised for suspected sepsis [38].…”

Section: Topical Treatmentsmentioning

confidence: 99%

Serious adverse effects of unconventional therapies for children and adolescents: a systematic review of recent evidence

Ernst¹

2003

Eur J Pediatr

141

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“…As direct side effects, chromate dermatitis due to a homeopathic preparation (19) and baboon syndrome with pronounced flexural erythema triggered by mercury (20) have been reported. A chemical burn caused by vinegar occurred in a newborn (21), but it seems doubtful whether this was really a “homeopathic” preparation.…”

Section: Side Effects Of Homeopathic Therapymentioning

confidence: 99%

Homeopathy in dermatology

Smolle

2003

Dermatol Ther

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Alternative methods are commonly used in patients with dermatologic diseases, with homeopathy being one of the most common. Homeopathy was developed by Samuel Hahnemann (1755-1843) and is based on the law of similars and the law of infinitesimals. It is a regulatory therapy where high dilutions of particular compounds are thought to induce a counterreaction in the organism. In dermatology, homeopathy is often used in atopic dermatitis, other forms of eczema, psoriasis, and many other conditions. To date, however, there is no convincing evidence for a therapeutic effect. There are only a few controlled trials, most of them with negative results. The few studies with positive results have not been reproduced. Acceptance by the patient seems largely based on counseling and emotional care rather than on objective responses to the homeopathic drugs.

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“…There have been various adverse effects of vinegar described in the literature. Some of these include corrosive injury to the esophagus, 2 hypokalemia associated with hyperreninemia and osteoporosis, 3 chemical burns to the dermis of an infant, 4 and one documented case of pancreatitis with 150 mL ingestion of 24% acetic acid 5 …”

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confidence: 99%

Natural Therapies—when Ignorance Is Not Bliss!!

Varvarelis¹,

Khallafi²,

Pappachen³

et al. 2007

J American Geriatrics Society

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significantly greater degree of hypoxia than the control subjects. The magnitude of ODI was not different between middle-aged and elderly patients with OSAS.Circulating AM levels in middle-aged and elderly patients with OSAS were significantly greater than in the ageand BMI-matched controls, although neither age nor sex affected them (Table 1). nCPAP treatment significantly decreased the higher levels of circulating AM in the patients irrespective of age and sex. After 3 months of treatment with nCPAP, AM levels in elderly patients (26.5 AE 2.4 pg/ mL) were not different from those of middle-aged patients (24.7 AE 2.1 pg/mL).These results indicated that plasma AM levels were higher in middle-aged and elderly patients with OSAS and could be deceased with nCPAP treatment, regardless of age and sex. The augmented increase in AM caused by severe nocturnal hypoxemia and oxidative stress due to OSA may overcome the age-dependent increase of AM levels in middle-aged and elderly patients with OSAS. Because AM is reported to induce cell surface expression of adhesion molecules, including E-selectin, vascular cell adhesion molecule-1, and intercellular adhesion molecule-1 (ICAM-1), on human endothelial cells, the higher level of AM is one of the mechanisms of higher levels of ICAM-1 in patients with OSAS. 10 The current study also indicates that treatment with nCPAP may be effective for the prevention of cardiovascular complications in elderly patients with OSAS.

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Chemical Burn Caused by Topical Vinegar Application in a Newborn Infant

Cited by 24 publications

References 15 publications

Serious adverse effects of unconventional therapies for children and adolescents: a systematic review of recent evidence

Serious adverse effects of unconventional therapies for children and adolescents: a systematic review of recent evidence

Homeopathy in dermatology

Natural Therapies—when Ignorance Is Not Bliss!!

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