Chemical Changes Produced in Isotonic Solutions of Sodium Sulfate and Sodium Chloride by the Small Intestine of the Dog

THE ABSORPTION OF SUGARS AND WATER FROM RAT INTESTINE IN VIVO

“…A similar variation among individual animals has been found by others. For example, a day-to-day variability was noticed in the values found for the fluxes of isotopic Na at all levels of the small intestine of the dog by Visscher, Varco, Carr, Dean and Erickson [1944], and a similar variation can be seen in other data for dog intestine given by Bucher, Anderson and Robinson [1950].…”

Action of aldosterone upon the intestinal transport of potassium, sodium, and water.

“…The reason for this remains obscure. It may be that the variability in the rates of sodium transport, encountered by most workers in this field (Visscher et al, 1944 a and b;Bucher, Anderson, and Robinson, 1950;Curran and Solomon, 1957;Berger, Ranzaki, Homer, and Steele, 1959;Shields, 1965a), obscured any change in the intestinal handling of sodium produced by aldosterone. Another reason may be that just as the effect of mineralocorticoids on the renal excretion of sodium is difficult to demonstrate in acute experiments in a normal dog (Barger, Berlin, and Tulenko, 1958), so also is their action upon the bowel.…”

Gastrointestinal Water and Electrolytes. III. The Equilibration of Radiobromide in Gastrointestinal Contents and the Proportion of Exchangeable Chloride (Cle) in the Gastrointestinal Tract1

“…At the aboral end of the bowel, chloride movement is oriented from gut to blood. Isotonic chloride solutions placed in the ileum or proximal colon show consistent diminution in chloride concentration and a reciprocal rise in bicarbonate concentration, while the sum of the concentrations of these anions remains unchanged (27,32,33). Taken together, these observations justify the identification of intraluminal chloride as a distinct subdivision of total extracellular chloride.…”