Chemical  characterization, antioxidant  and  antibacterial activity of  Moroccan Crocus sativus L petals and leaves

Jadouali, Si Mohamed; Atifi, Hajar; Bouzoubaâ, Zakia; Majourhat, Khalid; Gharby, Saïd; Achemchem, Fouad; Elmoslih, A.; Laknifli, Abdellatif; Mamouni, Rachid

doi:10.26872/jmes.2018.9.1.14

Cited by 23 publications

(23 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Results of the polyphenols assay of the leaf extract using Folin-Ciocalteu reagent revealed that the leaf extract had a phenolic content of 22.416 mg Gal/g dry weight, with a TFC of 77.21 mg QE/g dry weight. Our results are in consistent with the results reported by Jadouali et al [30] describing the presence of phenolic and flavonoid in leaves extract of saffron. These differences between studies can be attributed to various factors such as genotypic and environmental differences within saffron species and methods used for extract preparation.…”

Section: Preliminary Phytochemical Assaysupporting

confidence: 94%

Green synthesis, characterization, and biological activities of saffron leaf extract‐mediated zinc oxide nanoparticles: A sustainable approach to reuse an agricultural waste

Rahaiee

Ranjbar

Azizi

et al. 2020

Applied Organom Chemis

View full text Add to dashboard Cite

To increase the profitability and sustainability of agricultural waste, a facile green approach was established to synthesize zinc oxide nanoparticles (ZnO NPs) using saffron leaf extract as a reducing and stabilizing agent. Structural characteristics of NPs were investigated by X-ray diffraction (XRD), Fouriertransform infrared (FTIR), field emission scanning electron microscopy (FESEM), and UV-Visible (UV-Vis) spectroscopy. Characterization results revealed that ZnO NPs is highly crystalline with a hexagonal wurtzite structure and spherical particles with diameter less than 50 nm, as confirmed by XRD and FESEM techniques. UV-Vis absorption spectra depicted an absorption peak at 370 nm, which confirms the formation of ZnO NPs. FTIR spectral analysis confirmed the presence of functional groups and metal oxygen groups. The biological activities of ZnO NPs were also investigated. The antibacterial effect of ZnO NPs was investigated against selected food pathogens (Salmonella Typhimurium, Listeria monocytogenes, and Enterococcus faecalis). The study results prove that the green synthesized ZnO NPs show enhanced antibacterial activity against S. Typhimurium when compared with other strains. A dose-dependent free radical scavenging activity was observed for ZnO NPs in both 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) and fluorescence recovery after photobleaching (FRAP) assays. The ZnO NPs were evaluated for their photocatalytic activity during the degradation of methylene blue (MB) dye in aqueous solutions. The maximum removal of MB achieved was 64% with an initial ZnO NP concentration of 12 mg/mL under UV light. The present study revealed that the agricultural waste (saffron leaf) provides a simple and eco-friendly option to sustainably synthesize ZnO NPs for use as a photocatalyst. In addition, this is the first report on saffron leaf-mediated synthesis of ZnO NPs.

show abstract

Section: Preliminary Phytochemical Assaysupporting

confidence: 94%

Green synthesis, characterization, and biological activities of saffron leaf extract‐mediated zinc oxide nanoparticles: A sustainable approach to reuse an agricultural waste

Rahaiee

Ranjbar

Azizi

et al. 2020

Applied Organom Chemis

View full text Add to dashboard Cite

show abstract

“…Goli et al [8] and Termentzi and Kokkalou [28], respectively, reported total phenolic contents of 3.35 and 1.38 mg/g for Iranian saffron petal. Significantly greater amounts of total phenolic components (65.34 mg of GAE/g of powder extract) and flavonoids (60.64 mg CE/g of dry plant material) have been reported by Jadouali et al [29]. The reasons for the differences between our reported values and that of other researchers are probably attributed to the genetic variation, ecological conditions and/or the differences in the extraction method.…”

Section: Discussioncontrasting

confidence: 67%

The effect of adding ethanolic saffron petal extract and vitamin E on growth performance, blood metabolites and antioxidant status in Baluchi male lambs

Alipour¹,

Vakili²,

Mesgaran³

et al. 2019

Asian-Australas J Anim Sci

View full text Add to dashboard Cite

ObjectiveThis study investigated the effects of the administration of ethanolic saffron petal extract (SPE) and vitamin E (Vit E) on growth performance, blood metabolites and antioxidant status in Baluchi lambs.MethodsThirty-two Baluchi male lambs (35.22±5.75 kg) were randomly divided into 4 groups. The 1st (control), 2nd (injectable saffron petal extract [ISPE]), and 3rd (Vit E) groups were respectively injected subcutaneously with either physiological saline (5 mL), SPE (25 mg/kg body weight [BW]) or DL-α-tocopheryl acetate (225 IU) once a week. An oral dose of SPE (500 mg/kg BW) was also administered to the 4th group (oral saffron petal extract [OSPE]). Feed intake and BW were measured for 42 days and blood samples were taken on days 1, 14, 28, and 42. The lambs were slaughtered, and tissue samples were taken.ResultsGrowth performance and many blood metabolites were not affected (p>0.05) by the treatments. Cholesterol of plasma in the ISPE and Vit E groups was similar and less (p< 0.01) than both the OSPE and control groups. Although there was no significant difference between the control and other groups for plasma triglyceride, the ISPE group showed lower (p<0.05) triglyceride than the OSPE and Vit E groups. The highest (p<0.01) plasma glutathione peroxidase (GPx) was detected in the OSPE group, while the ISPE and Vit E groups showed higher (p<0.01) superoxide dismutase (SOD) of plasma than the control. Malondialdehyde of plasma in the ISPE group was lower (p<0.05) than the OSPE. No differences (p>0.05) were observed among the groups for antioxidant status of both longissimus dorsi muscle and liver. However, the activity of GPx in the kidney and heart, as well as SOD activity in the kidney, were influenced (p≤0.01) by the treatments.ConclusionAdding ethanolic SPE improved antioxidant status and lowered lipids oxidation in lambs. The SPE and Vit E demonstrated similar effects on antioxidant status in lambs.

show abstract

“…Bioactive compounds from petals have shown antinociceptive, anti-inflammatory [ 31 ], cytotoxic, antimicrobial, antioxidant, antidiabetic [ 32 ], antiobesity [ 33 ], antidepressant [ 34 ], anticancer, antityrosinase properties, as well as reduce blood pressure and contractility [ 35 ]. Several phenolic compounds from saffron leaves have been identified, showing antibacterial [ 36 , 37 ], anticancer [ 30 ], antioxidant, and metal ion chelating activities [ 37 , 38 ]. Likewise, bioactive constituents in saffron corm, such as proteoglycans, revealed to have a cytolytic effect on human tumor and plant cells and triterpenoid saponins on fungicidal and anticancer activities [ 30 ].…”

Section: Introductionmentioning

confidence: 99%

Potential Nutraceutical Benefits of In Vivo Grown Saffron (Crocus sativus L.) As Analgesic, Anti-inflammatory, Anticoagulant, and Antidepressant in Mice

Khan

Muhamad

Ismail

et al. 2020

Plants

View full text Add to dashboard Cite

Crocus sativus, a medicinally important herbaceous plant, has been traditionally used to cure coughs, colds, insomnia, cramps, asthma, and pain. Moreover, the therapeutic applications of saffron include its immunomodulatory and anticancer properties. The current experimental analysis was performed to explore the potential nutraceutical efficacy of corm, leaf, petal, and stigma of saffron ethanolic extracts as analgesic, anti-inflammatory, anticoagulant, and antidepressant using hot plate, carrageenan-induced paw edema, capillary tube and forced swim test, respectively in mice. The results indicated that among all the extracts, stigma ethanolic extract (SEE) represented maximum latency activity (72.85%) and edema inhibition (77.33%) followed by petal ethanolic extract (PEE) with latency activity and edema inhibition of 64.06 and 70.50%, respectively. Corm ethanolic extract (CEE) and leaf ethanolic extract (LEE) displayed mild analgesic activity of 22.40% and 29.07%, respectively. Additionally, LEE (53.29%) and CEE (47.47%) exhibited mild to moderate response against inflammation. The coagulation time of SEE (101.66 s) was almost equivalent to the standard drug, aspirin (101.66 s), suggesting a strong anticoagulant effect followed by PEE (86.5 s). LEE (66.83 s) represented moderate inhibitory effect on coagulation activity while CEE (42.83 s) showed neutral effect. Additionally, PEE and SEE also expressed itself as potential antidepressants with immobility time ≤76.66 s, while CEE (96.50 s) and LEE (106.83 s) indicated moderate to mild antidepressant efficacy. Based on the in vivo activities, saffron extract, particularly SEE and PEE, can be used as a potential nutraceutical and therapeutic agent due to its significant pharmacological activities.

show abstract

Chemical characterization, antioxidant and antibacterial activity of Moroccan Crocus sativus L petals and leaves

Cited by 23 publications

References 12 publications

Green synthesis, characterization, and biological activities of saffron leaf extract‐mediated zinc oxide nanoparticles: A sustainable approach to reuse an agricultural waste

Green synthesis, characterization, and biological activities of saffron leaf extract‐mediated zinc oxide nanoparticles: A sustainable approach to reuse an agricultural waste

The effect of adding ethanolic saffron petal extract and vitamin E on growth performance, blood metabolites and antioxidant status in Baluchi male lambs

Potential Nutraceutical Benefits of In Vivo Grown Saffron (Crocus sativus L.) As Analgesic, Anti-inflammatory, Anticoagulant, and Antidepressant in Mice

Contact Info

Product

Resources

About