Chemical composition and acetylcholinesterase inhibitory potential, in silico, of Myrciaria floribunda (H. West ex Willd.) O. Berg fruit peel essential oil

Barbosa, Deyzi Caroline da Silva; Holanda, Vanderlan Nogueira; Assis, Caio Rodrigo Dias; Aguiar, Júlio César de Oliveira Farias de Ribeiro; doNascimento, Pedro Henrique; Silva, Welson Vicente da; Navarro, Daniela Maria do Amaral Ferraz; Silva, Márcia Vanusa da; Lima, Vera Lúcia de Menezes; Correia, Maria Tereza dos Santos

doi:10.1016/j.indcrop.2020.112372

Cited by 34 publications

(27 citation statements)

References 78 publications

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“…For accesses AC67, AC132, AC92, AC160 and AC137, the main compounds were α-muurolene (21.04%), α-longipinene (24.21%), patchoulene (32.56%), caryophyllene (48.51%) and γ-selinene (58.18%), respectively. Similar results were reported by Silva Barbosa et al [ 26 ] by identifying the chemical composition of the essential oil of the peel of fruits of Myrciaria floribunda . A total of 26 compounds were identified, most of them belonging to the sesquiterpenes class—notably γ-cadinene (15.69%), γ- muurolene (6.21%), α-selinene (6.11%), α-muurolene (6.11%), caryophyllene (5.54%) and α-copaene (5.02), as they were the major compounds.…”

Section: Resultssupporting

confidence: 90%

Chemical Physical Characterization and Profile of Fruit Volatile Compounds from Different Accesses of Myrciaria floribunda (H. West Ex Wild.) O. Berg through Polyacrylate Fiber

et al. 2021

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Among the many species of native fruit of Brazil that have been little explored, there is Myrciaria floribunda (also known as rumberry, cambuizeiro, or guavaberry), a species with significant variability, which has fruits of different colors (orange, red, and purple) when ripe. The physical-chemical characteristics evaluated were fruit weight (FW), seed weight (SW), pulp weight (PW), number of seeds (NS), longitudinal diameter (LD), transverse diameter (TD), format (LD/TD), hydrogen potential (pH), soluble solids (SS), titratable acidity (TA), and ratio (SS/TA); further, the volatile organic compounds (VOCs) of nine accesses of rumberry orchards were identified. The averages of the variables FW, SW, PW, NS, LD, TD, shape, and firmness were 0.76 g, 0.22 g, 0.54 g, 1.45, 10.06 mm, 9.90 mm, 1.02, 2.96 N, respectively. LD/TD data showed that the fruits have a slightly rounded shape (LD/TD = 1). The averages for pH, SS, TA, and SS/TA were 3.74, 17.58 Brix, 4.31% citric acid, and 4.31, respectively. The evaluated parameters indicated that the fruits can be consumed both in natura and industrialized, with the red-colored fruits presenting a good balance of SS/TA, standards demanded by the processing industries. Thirty-six VOCs were identified, with emphasis on the sesquiterpenes. Caryophyllene (21.6% to 49.3%) and γ-selinene (11.3% to 16.3%) were the most predominant compounds in rumberry fruits.

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Section: Resultssupporting

confidence: 90%

Chemical Physical Characterization and Profile of Fruit Volatile Compounds from Different Accesses of Myrciaria floribunda (H. West Ex Wild.) O. Berg through Polyacrylate Fiber

et al. 2021

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“…The citrus aroma with a spicy touch of α-selinene sesquiterpene is the most representative component of the cluster, with 1.7% of the total profile emitted by ‘Otto Andersen’ jabuticabas. α -selinene is considered to be one of the characteristic compounds of the aroma of Myrtaceae family species [ 30 , 31 , 32 ], but has also been identified in other botanical families, such as Cyperaceae and Lamiaceae [ 33 , 34 ].…”

Section: Resultsmentioning

confidence: 99%

Volatile Compounds and Physicochemical Quality of Four Jabuticabas (Plinia sp.)

et al. 2020

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The jabuticaba is a native Brazilian fruit that has aroused worldwide interest in terms of its nutritional composition and biological activity. However, research on the profile of volatile compounds (VOCs) emitted by these fruits is rare. This study presents the first identification of VOCs from four jabuticaba species. The aim of the study was to characterize the aromatic profile of the following species: ‘Sabará’ (Plinia jaboticaba), ‘Escarlate’ (Plinia phitrantha × Plinia cauliflora), ‘Otto Andersen’ (Plinia cauliflora), and ‘Esalq’ (Plinia phitrantha). The analysis was performed by headspace solid-phase microextraction combined with gas chromatography/mass spectrometry (SPME-GC-MS). Multivariate analysis techniques applying the partial least squares-discriminant analysis (PLS-DA) and heatmap were used to compare the results. Fruit quality parameters were determined in terms of fresh mass (g), skin color, soluble solids, and titratable acidity. A total of 117 VOCs was identified including terpenoids, esters, alcohols, aldehydes, alkanes, ketones, and carboxylic acids, with 36 VOCs common to all four species. Terpenes were the majority for all jabuticabas with smaller contributions from other volatile classes, especially β-cubebene, β-elemene, and D-limonene for the ‘Otto Andersen’ jabuticaba.

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“…This lack of anticholinesterase activity can be explained by EO composition, in which the active compounds reported in Reference [53], as well as others contained in different EOs, proved to have such an effect; α-pinene and 1,8-cineole [54] were completely absent or present at very low levels, as were δand γ-cadinene [55]. Indeed, here, β-caryophyllene, but not α-humulene and β-myrcene, showed mild anticholinesterase activity; however, its content (less than 15%), as well as a potential antagonist effect exerted by other compounds [56] resulted in no AChE inhibition by EO.…”

Section: Discussionmentioning

confidence: 99%

“…Different from what was recently reported for water and ethanol extracts obtained by hop cones [ 53 ], hop EO showed negligible anticholinesterase activity; this strongly suggesting that the inhibition of AChE cannot be the mechanism of action by which EO exerts its toxic activities. This lack of anticholinesterase activity can be explained by EO composition, in which the active compounds reported in Reference [ 53 ], as well as others contained in different EOs, proved to have such an effect; α-pinene and 1,8-cineole [ 54 ] were completely absent or present at very low levels, as were δ- and γ-cadinene [ 55 ]. Indeed, here, β-caryophyllene, but not α-humulene and β-myrcene, showed mild anticholinesterase activity; however, its content (less than 15%), as well as a potential antagonist effect exerted by other compounds [ 56 ] resulted in no AChE inhibition by EO.…”

Section: Discussionmentioning

confidence: 99%

Biological Activity of Humulus lupulus (L.) Essential Oil and Its Main Components against Sitophilus granarius (L.)

et al. 2020

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Besides its use in the brewing industry, hop cones appear as a powerful source of biologically active compounds, already checked for their putative anticancer, antimicrobial, and other bioactivities. Conversely, hop use in pest control remains to date under-investigated. Therefore, the biological activity of hop essential oil (EO) and its main constituents was investigated here against Sitophilus granarius. Adult contact toxicity was found 24 h after treatment with hop EO (LD50/LD90 13.30/40.23 µg/adult), and its three most abundant components, α-humulene, β-myrcene, and β-caryophyllene (LD50/LD90 41.87/73.51, 75.91/126.05, and 138.51/241.27 µg/adult, respectively); negligible variations at 48 h, except for α-humulene (LD50/LD90 26.83/49.49 µg/adult), were found. The fumigant toxicity of the EO and terpenes was also checked: in the absence of wheat grains, β-myrcene showed the highest inhalation toxicity (LC50/LC90 72.78/116.92 mg/L air), whereas α-humulene, β-caryophyllene, and the EO induced similar values (LC50/LC90 about 130/200 mg/L air); with the exception for EO, the wheat presence increased (30–50%) LC50/LC90 values. Moreover, EO and terpenes were perceived by insect antennae and elicited repellent activity. Only β-caryophyllene showed an anticholinesterase effect, this suggesting that different mechanisms of action should be responsible for hop EO toxicity. Therefore, hop EO appears suitable for developing control means against this pest.

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Chemical composition and acetylcholinesterase inhibitory potential, in silico, of Myrciaria floribunda (H. West ex Willd.) O. Berg fruit peel essential oil

Cited by 34 publications

References 78 publications

Chemical Physical Characterization and Profile of Fruit Volatile Compounds from Different Accesses of Myrciaria floribunda (H. West Ex Wild.) O. Berg through Polyacrylate Fiber

Chemical Physical Characterization and Profile of Fruit Volatile Compounds from Different Accesses of Myrciaria floribunda (H. West Ex Wild.) O. Berg through Polyacrylate Fiber

Volatile Compounds and Physicochemical Quality of Four Jabuticabas (Plinia sp.)

Biological Activity of Humulus lupulus (L.) Essential Oil and Its Main Components against Sitophilus granarius (L.)

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