Chemical Composition and Anti-Inflammatory, Cytotoxic and Antioxidant Activities of Essential Oil from Leaves of Mentha piperita Grown in China

Sun, Zilong; Wang, Huiyan; Wang, Jing; Zhou, Lianming; Yang, Peng

doi:10.1371/journal.pone.0114767

Cited by 144 publications

(153 citation statements)

References 25 publications

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“…Similarly, the cytotoxic efect of Mentha piperita essential oil was assessed against four human cancer cells. It was found to be signiicantly active against human lung carcinoma SPC-A1, human leukemia K562, and human gastric cancer SGC-7901 cells, with IC 50 values of 10.9, 16.2, and 38.8 μg/mL, respectively [138].…”

Section: Cytotoxicitymentioning

confidence: 99%

“…The acetonic extract and essential oil of peppermint act as scavengers of hydroxyl radical (•OH) [25,138], the hydroalcoholic extract of M. piperita [139] and peppermint essential oil [140] as scavengers of nitric oxide (•NO), and the ethanolic and water extracts of M. pulegium [141] as scavengers of hydrogen peroxide (H 2 O 2 ). Besides, diferent fractions of the ethanol extract of M. spicata [142]; the ethanolic extracts from M. spicata, M. pulegium, and M. rotundifolia [99]; the methanolic extract of M. pulegium [68,143] and M. longifolia [68] were shown to quench superoxide…”

Section: Antioxidant Activitymentioning

confidence: 99%

“…The DPPH test, a test widely used to measure the ability to donate hydrogen atoms [41], was applied to measure the antioxidant capacities of Mentha species extracted by diferent solvent systems; these include the ethanol extracts of M. longifolia, M. piperita [144], M. pulegium [73,99,141,144], M. spicata, and M. rotundifolia [96,144]; the methanol extracts from M. pulegium [68,69,143,145], M. longifolia [68,93], M. aquatica, M. arvensis, M. piperita, M. rotundifolia, and M. villosa [145]; the water extracts from M. pulegium [69,73,141]; and the acetonic extracts from peppermint [25] and M. spicata [146]. DPPH was also used to evaluate the antioxidant activity of the essential oils from M. aquatica [92], M. longifolia [6,68,92,93], M. spicata [6,46,51], M. pulegium [68,69,72,73], M. rotundifolia [89,147], and M. piperita [46,92,138,140].…”

Section: Antioxidant Activitymentioning

confidence: 99%

“…• NO) and prostaglandin E2 (PGE2) production in lipopolysaccharide (LPS)-activated RAW 264.7 macrophages [138]. Lv et al [25] using J774A.1 mouse macrophage cells showed that peppermint extracts were eicient in inhibiting IL-1 and COX-2 expression and have inhibitory efect on IL-6 and MCP-1 (IC 50 s ranging from 50 to 100 μg/mL).…”

Section: Anti-inlammatory Propertiesmentioning

confidence: 99%

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Chemical Composition and Biological Activities of Mentha Species

Brahmi¹,

Madani²,

Chibane³

et al. 2017

Aromatic and Medicinal Plants - Back to Nature

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The genus Mentha L. (Lamiaceae) is distributed all over the world and can be found in many environments. Mentha species, one of the world's oldest and most popular herbs, are widely used in cooking, in cosmetics, and as alternative or complementary therapy, mainly for the treatment of gastrointestinal disorders like latulence, indigestion, nausea, vomiting, anorexia, and ulcerative colitis. Furthermore, it is well documented that the essential oil and extracts of Mentha species possess antimicrobial, fungicidal, antiviral, insecticidal, and antioxidant properties. The economic importance of mints is also evident; mint oil and its constituents and derivatives are used as lavoring agents throughout the world in food, pharmaceutical, herbal, perfumery, and lavoring industry. To provide a scientiic basis for their traditional uses, several studies have been conducted to determine the chemical composition of mints and assess their biological activities. This chapter describes the therapeutic efects and uses of Mentha species and their constituents, particularly essential oils and phenolic compounds; some additional biological activities will also be considered.

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Section: Cytotoxicitymentioning

confidence: 99%

Section: Antioxidant Activitymentioning

confidence: 99%

Section: Antioxidant Activitymentioning

confidence: 99%

Section: Anti-inlammatory Propertiesmentioning

confidence: 99%

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Chemical Composition and Biological Activities of Mentha Species

Brahmi¹,

Madani²,

Chibane³

et al. 2017

Aromatic and Medicinal Plants - Back to Nature

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“…Basil, one of the most important and wildly used spices, has been shown to have antioxidant, antibacterial, and anti-diarrheal activities [1]. Mint (Mentha piperita) has anti-inflammatory, cytotoxic and antioxidant activities [2]. Sage (Salvia officinalis) has a savory, peppery flavor and is used as condiment.…”

Section: Introductionmentioning

confidence: 99%

Comparative Characterization of Basil, Mint and Sage Extracts

Bleiziffer¹,

Mesaros²,

Suvar³

et al. 2017

Studia UBB Chemia

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ABSTRACT. Aromatic plants are widely used in food preparation for aroma and fragrance, but they are also a good source of amino acids and fatty acids. Three indigenous species, Basil (Ocimum basilicum), mint (Mentha piperita) and sage (Salvia officinalis) which are traditionally used in medicine and food, were characterized and compared in terms of volatile extracts, amino acids, fatty acids contents and antioxidant activities. The gas chromatographic-mass spectrometry (GC-MS) method is a suitable technique for the characterization of the compounds of the herbs extracts. Antioxidant activity was measured using extracts ability to scavenge DPPH radicals. Linalool was found the major compound in basil, menthol in mint and α-thujone in sage. The dominant amino acids identified in the plants extracts were glutamic acid and aspartic acid in basil and mint, while proline was found in high concentration in sage and mint. The total free fatty acids (TFA) were highest in mint, followed by sage and basil. The essential omega 3 alpha-linolenic acid (ALA) was identified in all three extracts. All samples exhibited antioxidant activity, sage extract having the highest antioxidant activity.

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