Chemical composition and antimicrobial activitiy of the essential oils of Thevetia peruviana and Plumeria rubra cultivated in Egypt

Abstract

Thevetia peruviana and Plumeria rubra (family Apocyanaceae) are shrubs cultivated in Egypt for ornamental purposes. This study was done to compare the volatile oils of T. peruviana and P. rubra which were prepared by using the hydrodistillation method from fresh flowers and leaves of each plant. Identification and quantification of the oil components were carried out by GC/MS analysis. The major components of T. peruviana flowers oil were Nonadecane (37.69 %), followed by 1-Nonylcycloheptane (18.39%), while Perilla alcohol (20.49%), β-ylangene(10.62%) and β-Elemene (7.19%) were predominant in the leaves oil. On the other hand, the major constituents of P. rubra flowers oil were Methyl dihydroepi-jasmonate (35.41%), Linalool (14.31%) and Methyl jasmonate (11.99%), while 1-Nonylcycloheptane (32.16%) and Menthol (17.89%) were of highest abundance in the leaves oil. Also, the antimicrobial activity was investigated against Staphylococcus aureus ATCC 4175, Escherichia coli ATCC 10536, Pseudomonas aeruginosa CNCM A21, and Candida albicans ATCC 60193. The minimum inhibitory concentrations (MIC) were determined and compared with those of standard antibiotics (Ofloxacin and Amphotericin B), the tested oils showed a good inhibitory effect against the investigated microbial strains with a minimum inhibitory concentration (MIC) range of 25 to 300 µg/mL except for the P. rubra leaves oil, which showed no activity against Pseudomonas aeruginosa.

Bioassay-Guided Phytochemical Analyses and Antimicrobial Potentials of the Leaf Extract of Clematis hirsuta Perr. and Guill. Against Some Pathogenic Bacteria and Fungi

“…The third most abundant compound found in the analysis of the extract is nonyl cyclo-heptane, which is an alkyl-substituted alicyclic compound. It is a hydrocarbon contained in flowers and leaves of plants such Thevetia peruvian and Plumeria rubra ; 41 essential oils from these plants have shown antimicrobial activity against S. aureus, E. coli, P. aeruginosa and C. albicans . 41 Cycloheptane has also been detected in other plants, such as Piper guineense and Cnidoscolus quercifolius .…”

“…It is a hydrocarbon contained in flowers and leaves of plants such Thevetia peruvian and Plumeria rubra; 41 essential oils from these plants have shown antimicrobial activity against S. aureus, E. coli, P. aeruginosa and C. albicans. 41 Cycloheptane has also been detected in other plants, such as Piper guineense and Cnidoscolus quercifolius. 42,43 According to an extensive literature survey conducted as part of this study, we found that protoanemonin is the major volatile compound in plants belonging to the Ranunculaceae family, along with thirty-five other components.…”

Polyphenolics of Plumeria rubra L.and cytotoxic activities against lung, colon, and breast carcinoma

“…Anticancer screening results demonstrated in Figures (4)(5)(6) showed that the total methanol extract of P. rubra exerted a promising anticancer activity against lung carcinoma A-549 cell line to the standard drug cisplatin, with IC 50 value (41.72 μg/ml). On the other hand, the extract of P. rubra exhibits a moderate anticancer activity against colon carcinoma HCT-116 cell line IC 50 value was (57.62 μg/ml).…”

“…Plumeria, a genus in Apocyanaceae family, are usually cultivated in gardens, for their showy and fragrant flowers [4]. Plumeria rubra is an ornamental plant, a small, deciduous spreading tree having a height of about 7-8 m. P. rubra possesses a long history, and because it was once grown close to temples, people would often refer to it as a "temple tree."…”