Chemical Composition and Antimicrobial Activity ofRosa damascenaMill Essential Oil

Abstract

Rosa damascena Mill. a plant from Rosaceae family is traditionally used for treatment of many disorders especially against infectious diseases. The antimicrobial activity of R. damascena oil was determined against a large number of microorganisms including Gram positive and Gram negative bacteria, yeast and filamentous by micro broth dilution assay. The oil was analyzed by GC and GC-MS. Chemical composition of oil revealed the presence of β-citronellol (48.2 %), geraniol (17.0 %), β-phenylethyl benzoate (5.4 %) and phenyl ethyl alcohol (5.1 %) as the main components. The MIC values of oil were in the ranges of 0.125-1 μl/ml. Enterococcus faecalis, Enterococcus faecium, Salmonella typhimurium and Pseudomonas aeruginosa were less sensitive to R. damascena oil. The oil exhibited the antimicrobial activity against a large number of microorganisms especially against Proteus vulgaris and Klebsiella pneumonia. This oil could be used as a natural antimicrobial agent in treatment of infectious diseases; more clinical studies should be done for demonstration of its efficacy.

Rosa damascena as holy ancient herb with novel applications

“…Vesicatoria 23 , Chromobacterium violaceum and Erwinia carotovora strains, 13 Staphylococcus aureus , 24 Bacillus cereus , Staphylococcus epidermidis , Pseudomonas fluorescens . 18 Pseudomonas aeruginosa 10 , 24 , 25 , Escherichia coli , Proteus vulgaris , Klebsiella pneumoniae , Candida albicans , Enterococcus faecalis , 24 Enterococcus faecium and Salmonella typhimurium 24 , 25 were less sensitive to rose essential oil. Bulgarian rose oil has been shown no antimicrobial activity.…”

Morphological and anatomical evaluation of herbal drugs sold under the name of Gül (Rosa damascena Mill.) in Turkey

“…It is reported that its flowers especially contain essential oil, anthocyanin, flavonoid, tannin, and phenolic acid [13][14][15][16][17][18][19]. It has displayed diverse biological and pharmacological activities.…”

“…Anti-inflammatory, neuroprotective, antidepressant, antidiabetic, antiplasmodial effects of them have been shown in animal models [22,[24][25][26][27]. Biological activities such as anticancer, anticholinesterase, anti-inflammatory, antimicrobial, antioxidant of essential oils obtained from the flowers have been studied [15,18,[27][28][29].…”

Oxidative stability of UV irradiated and X-rayed soybean oil incorporated with rose oil

“…This fragrant rose is a member of a few rose species produced commercially for oil, hips, concrete, absolute, and rose water (Mahboubi, 2016). The available literature has revealed that rose oil shows antioxidant (Yassa et al, 2009), antibacterial (Ulusoy et al, 2009), antifungal (Mahboubi et al, 2011) and anticancer (Zu et al, 2010) activities. The components of rose oil vary in different parts of the world.…”