Chemical Composition and Biological Activities of Essential Oil from Ocimum basilicum L. Collected in Dak Lak, Vietnam

Abstract

The essential oil, second metabolites, extracts and other products of O. basilicum have been discovered to play multiple roles as antioxidant, anti-inflammatory, antimicrobial, antifungal, insect-repelling, anticonvulsant, hypnotic, anticancer activities. 4,[8][9][10][11][12][13][14][15][16] Basil has been cultivated and popular in Vietnam since 1975. A number of provinces in Vietnam have grown on a large scale to store essential oils for the domestic and foreign aromatics industries. However, studies on this species' chemical composition and biological properties have not been explored to date. Quynh Anh et al. reported the Basil essential oil from Thua Thien Hue Province contained crucial chemical components, namely p-allylanisole (49.09%), aromadendrene (8.27%), and trans-ocimene (5.71%). 17 The results further revealed that the essential oil had a relatively low antioxidant capacity, with an IC50 value of 35.89 μg/mL. 17 However, it exhibited antibacterial effects by inhibiting the growth of two bacterial strains, E. coli, and Salmonella sp. The research highlights that the chemical compositions and biological activities of essential oils can vary significantly depending on the geographical locations and soil conditions where the plants are grown. This emphasizes the importance of considering the origin and environment when studying essential oils and their potential applications. In this study, the experimental work focused on extracting essential oil from O. basilicum. Following the extraction process, GC-MS was used to analyze and characterize the chemical composition of the essential oil. In addition, the antioxidant and antibacterial activities of this Basil oil were also investigated.

Molecular Characterization of Endophytic Fungi from the Leaves of Beruwas Laut (Scaevola taccada (Gaertn.) Roxb.) as Antibacterial Producer

“…Inhibition zone measurements were made for three sample replications, and the results were expressed as the mean of the three duplicate measurements. 23,24 Bioautographic TLC method The best chromatogram results were followed by a TLC-bioautography test on a Petri dish. Approximately 10 mL of the nutrient agar was added to a suspension of test bacteria (about 20 µL) and then homogenized.…”