Chemical Composition and Biological Activity of Essential Oils from <i>Aloe debrana</i> roots

Getahun, Tokuma; Sharma, Vinit; Gupta, Neeraj

doi:10.1080/0972060x.2020.1788996

Cited by 9 publications

(5 citation statements)

References 29 publications

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“…Similar composition of essential oils could also be spotted in some species outside of the Compositae family, e.g., in Cyclospermum leptophyllum (Pers.) Sprague ex Britton and P. Wilson (Apiaceae) and Aloe debrana Christian (Xanthorrhoeaceae) [ 41 , 42 ].…”

Section: Discussionmentioning

confidence: 99%

Composition of Essential Oils from Roots and Aerial Parts of Carpesium cernuum and Their Antibacterial and Cytotoxic Activities

et al. 2021

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Carpesium cernuum L., one of the two Carpesium species occurring in Europe, in the Far East and India, found use as a vegetable and a traditional medicinal remedy for several ailments. In the present study, compositions of essential oils distilled from roots and shoots of C. cernuum plants, cultivated in the open field, have been studied by GC-MS-FID supported by NMR spectroscopy. The analyses led to the identification of 120 compounds in total, of which 115 were found in aerial parts and 37 in roots of the plants. The major constituents found in the oil from shoots were: α-pinene (35%) and 2,5-dimethoxy-p-cymene (thymohydroquinone dimethyl ether, 12%), whereas 2,5-dimethoxy-p-cymene (55%), thymyl isobutyrate (9%) and thymol methyl ether (8%) predominated in the essential oil obtained from the roots. Antibacterial and cytotoxic activities of the essential oils distilled from C. cernuum were also tested. The essential oil from aerial parts of the plant demonstrated good inhibitory activity against Staphylococcus aureus ATCC 29213 and Escherichia coli ATCC 25922 (MIC: 15.6 μL/mL).

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Section: Discussionmentioning

confidence: 99%

Composition of Essential Oils from Roots and Aerial Parts of Carpesium cernuum and Their Antibacterial and Cytotoxic Activities

et al. 2021

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“…The new media (10 mL) were used to cultivate 100 μL of the test bacteria until they had a count of nearly 10E5 colony-forming units (cfu)/mL. Then the microbial suspension was injected in a volume of 100 μL on Mueller Hinton agar plates [17][18]. Discs made of 6 mm sterile filter paper were used to evaluate the extracts.…”

Section: Antimicrobial Activitymentioning

confidence: 99%

Evaluation of Phytochemical Properties and Biological Activities of Leaf Extracts and Oil of <i>Petroselinum sativum</i> Collected from Algeria

Benmekhbi

Mosbah²,

Laamraoui³

et al. 2022

Indones. J. Chem.

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Indigenous medical professionals prescribe plant-based therapeutics for the handling of a range of maladies and use typical medical care at the preventive level. Oxidative stress, obesity, and multidrug resistance to pathogenic microorganisms are major challenges in the healthcare systems and pharmaceutical industries. This study aimed to screen phytoconstituents, estimate total phenol and flavonoid contents, and evaluate the antioxidant, and antimicrobial activities of Petroselinum sativum extracts and essential oil growing in Algeria. The antioxidant capacity of n-butanol, dichloromethane extracts and essential oil was determined by using DPPH radical scavenging method. All extracts were also evaluated against Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacterial species using the disk diffusion method. The leaves are pharmacologically active and related to the detected phytochemical components. In the proximate analysis, plant nutrients that are important for diverse pharmacological activities are found in the leaves. The ethyl acetate extract of P. sativum showed the highest phenol content while the n-butanol and ethyl acetate extracts gave high flavonoid contents at 144.44 ± 0.07 and 100.97 ± 0.04 mg/g, respectively. The antioxidant results demonstrate powerful free radical scavenging activity for three extracts. The activity reduced in the following order as concentration increased n-BuOH > AE > DCM.

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“…Approximately 83 Aloe plants occur in Eastern Africa [ 6 ], of which 46 grow naturally in dry and grasslands of Ethiopia with 16 of them being endemic [ 7 ]. Aloe debrana Christian is a stemless evergreen endemic medicinal Aloe plant of Ethiopia, which commonly grows in the areas of grassland on thin soil overlying basalt, usually on gentle slopes between 2,400 and 2,700 m above sea level in Shewa, Gojam, and Wello regions [ 4 , 8 ].…”

Section: Introductionmentioning

confidence: 99%

“…In Ethiopian traditional herbal medicines, A. debrana is used for the treatment of wounds, eye inflammation, malaria, excessive pain, gastrointestinal, and dermatological problems [ 8 ]. It is useful in water and soil conservation [ 9 ], to stop breastfeeding, and it was examined as good thickening agent for printing polyester and cotton with disperse dyes.…”

Section: Introductionmentioning

confidence: 99%

Antibacterial and Antioxidant Compounds from the Root Extract of Aloe debrana

Getahun,

Das,

Sil

et al. 2024

Evidence-Based Complementary and Alternative Medicine

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This study was conducted to isolate and identify the chemical compounds from the roots of Aloe debrana (L.) and evaluate their antioxidant and antibacterial activities. From the acetone (99.5%) extract of the roots of this plant, four anthraquinones, such as chrysophanol (1), asphodeline (2), aloesaponarin I (5), and laccaic acid D-methyl ester (6), and a new catechol derivative, 5-allyl-3-methoxybenzene-1,2-diol (3), were isolated and elucidated by different chromatographic and spectroscopic methods together with linoleic acid (4), respectively. Compounds 2, 3, and 4 were reported here for the first time from this plant and compound 3 from the genus Aloe. The compounds were evaluated for their antioxidant activity using H2O2 and DPPH assays and bactericidal activity against S. aureus and E. coli. Compounds 3 and 6 showed highest antioxidant activities with IC50 values of 19.38 ± 0.64 and 32.81 ± 0.78 μg/mL in DPPH, and 28.52 ± 1.08 and 27.31 ± 1.46 μg/mL in H2O2, respectively. The isolated compounds also demonstrated considerable activity towards S. aureus. Among these compounds, compound 3 exhibited the highest activity (91.20 ± 0.12% and 9.14 ± 0.93 mm at 1.0 mg/mL) against this bacterium. The overall results suggest that the isolated compounds may be considered as potential sources of the bioactive agents to be used in the pharmacological, food, and other industries. Moreover, their high sensitivity against S. aureus may also support the use of A. debrana plant in the traditional medicine to treat wounds. Therefore, the isolated compounds are responsible for medicinal properties of this plant.

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Chemical Composition and Biological Activity of Essential Oils from Aloe debrana roots

Cited by 9 publications

References 29 publications

Composition of Essential Oils from Roots and Aerial Parts of Carpesium cernuum and Their Antibacterial and Cytotoxic Activities

Composition of Essential Oils from Roots and Aerial Parts of Carpesium cernuum and Their Antibacterial and Cytotoxic Activities

Evaluation of Phytochemical Properties and Biological Activities of Leaf Extracts and Oil of <i>Petroselinum sativum</i> Collected from Algeria

Antibacterial and Antioxidant Compounds from the Root Extract of Aloe debrana

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