Chemical Composition and Cytotoxic and Antioxidant Activities of Satureja montana L. Essential Oil and Its Antibacterial Potential against Salmonella Spp. Strains

Abstract

The present study describes chemical composition as well as cytotoxic, antioxidant, and antimicrobial activities of winter savorySatureja montanaL. essential oil (EO). The plant was collected from south France mountain, and its EO was extracted by hydrodistillation (HD) and analysed by gas chromatography/mass spectrometry (GC/MS). Thirty-two compounds were identified accounting for 99.85% of the total oil, where oxygenated monoterpenes constituted the main chemical class (59.11%). The oil was dominated by carvacrol (53.35%),γ-terpinene (13.54%), and the monoterpenic hydrocarbonsp-cymene (13.03%). Moreover,S. montanaL. EO exhibited high antibacterial activities with strong effectiveness against several pathogenic food isolatedSalmonellaspp. includingS. enteritidiswith a diameter of inhibition zones growth ranging from 21 to 51 mm and MIC and MBC values ranging from 0.39–1.56 mg/mL to 0.39–3.12 mg/mL, respectively. Furthermore, theS. montanaL. EO was investigated for its cytotoxic and antioxidant activities. The results revealed a significant cytotoxic effect ofS. montanaL. EO against A549 cell line and an important antioxidant activity. These findings suggest thatS. montanaL. EO may be considered as an interesting source of components used as potent agents in food preservation and for therapeutic or nutraceutical industries.

Medicinal plants of the family Lamiaceae as functional foods - a review

“…antinociceptive and anti-inflammatory (Hajhashemi et al 2002); antibacterial (Dincer et al 2013); antioxidant (Yesiloglu et al 2013) leaves antimicrobial (Rota et al 2004);antibacterial (Nedorostova et al 2011;Sfeir et al 2013); cytotoxic, antioxidant, and antimicrobial (Miladi et al 2013); antioxidant and antimicrobial (Cavar et al 2008) leaves and flowered aerial part 42 Scutellaria baicalensis antioxidant and antiinflamatory (Seok et al 2016); cardiovascular, kidney, and liver diseases (Lai et al 2016) leaves 43 Scutellaria indica L. antitumour (Min et al 1997); antioxidant (Kim et al 2009) leaves 44 Sideritis scardica Griseb.…”

Evaluation Of Potential Cytotoxic Effects Of Herbal Extracts

“…Some of the most common classes are anthraquinons, polyphenolic compounds and triterpenoid saponins. The high content of polyphenolic compounds and anthraquinons is responsible for the antioxidant activity, which is associated with stronger cytotoxic activity (6,12). Several mechanisms have been involved in the anticancer activity of anthraquinons.…”

Biopreservation of meat using the essential oil from Hyptis suaveolens Poit. (Lamiaceae) in Burkina Faso

“…Oxygen-rich essential oils have a stronger anti-radical activity compared to hydrocarbon terpenes. This could explain the moderate antioxidant activity of the essential oil of H. suaveolens (Miladi et al, 2013).…”

“…One of the main problems in food industry is to ensure safe food preservation for consumers (Nessrien and Mohamed, 2007). To cope with the problems of oxidation and contamination of foodstuffs, new chemical compounds have often been used to prevent the deterioration of food (Nakahara et al, 2003a). Preservatives such as butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT) and tert-Butylhydroquinone (TBHQ) used in food preservation have been limited in several countries due to their undesirable toxicological and carcinogenic effects at short or long time (Rachid et al, 2010).…”