Chemical composition and evaluation of the anti-inflammatory and antinociceptive activities of Duguetia furfuracea essential oil: Effect on edema, leukocyte recruitment, tumor necrosis factor alpha production, iNOS expression, and adenosinergic and opioidergic systems

Saldanha, Aline Aparecida; Vieira, Letícia; Ribeiro, Rosy Iara Maciel de Azambuja; Thomé, Ralph Gruppi; Santos, Hélio Batista dos; Silva, Denise Brentan; Carollo, Carlos Alexandre; Oliveira, Flávio Martins de; Lopes, Débora de Oliveira; Siqueira, João Máximo de; Soares, Adriana Cristina

doi:10.1016/j.jep.2018.11.017

Cited by 23 publications

(20 citation statements)

References 76 publications

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“…The antinociceptive effect of a Duguetia furfuracea underground stem bark EO, composed mainly of (E)-asarone (21.9%), bicyclogermacrene (16.7%), 2,4,5-trimethoxystyrene (16.1%), α-gurjunene (15.0%), and cyperene (7.8%), was investigated. The results showed that the antinociceptive activity of this EO is possibly mediated by adenosinergic and opioidergic pathways and that its properties do not induce effects on motor coordination [13].…”

Section: Other Activitiesmentioning

confidence: 89%

“…The EO from the bark of the underground stem of Duguetia furfuracea, which is rich in (E)-asarone (21.9%), bicyclogermacrene (16.7%), 2,4,5-trimethoxystyrene (16.1%), α-gurjunene (15.0%), and cyperene (7.8%), was shown to have anti-inflammatory effects [13].…”

Section: Anti-inflammatory Activitymentioning

confidence: 99%

“…According to the review published by Fournier et al [10], the main volatile constituents of EOs from the Annonaceae species are monoterpene hydrocarbons in fruits and seeds, sesquiterpene hydrocarbons in leaves, and oxygenated sesquiterpenes in bark and roots. After this review (1999), several articles were made available in the literature showing the chemical and biological properties of EOs obtained from Annonaceae species [11][12][13][14]. In this context, the present work aims to carry out a systematic review of the essential oils of the Annonaceae species collected in Brazil in the last ten years, evaluating their chemical compositions and their potential biological activities.…”

Section: Introductionmentioning

confidence: 99%

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Essential Oils from Annonaceae Species from Brazil: A Systematic Review of Their Phytochemistry, and Biological Activities

Cascaes

Carneiro

Nascimento

et al. 2021

IJMS

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The present work involves a systematic review of the chemical composition and biological effects of essential oils from the Annonaceae species collected in Brazil from 2011 to 2021. Annonaceae is one of the most important botanical families in Brazil, as some species have economic value in the market as local and international fruit. In addition, the species have useful applications in several areas—for instance, as raw materials for use in cosmetics and perfumery and as medicinal plants. In folk medicine, species such as Annona glabra L. and Xylopia sericea A. St.-Hil. are used to treat diseases such as rheumatism and malaria. The species of Annonaceae are an important source of essential oils and are rich in compounds belonging to the classes of mono and sesquiterpenes; of these compounds, α-pinene, β-pinene, limonene, (E)-caryophyllene, bicyclogermacrene, caryophyllene oxide, germacrene D, spathulenol, and β-elemene are the most abundant. The antimicrobial, anti-inflammatory, antileishmania, antioxidant, antiproliferative, cytotoxic, larvicidal, trypanocidal, and antimalarial activities of essential oils from the Annonaceae species in Brazil have been described in previous research, with the most studies on this topic being related to their antiproliferative or cytotoxic activities. In some studies, it was observed that the biological activity reported for these essential oils was superior to that of drugs available on the market, as is the case of the essential oil of the species Guatteria punctata (Aubl.) R. A. Howard., which showed a trypanocidal effect that was 34 times stronger than that of the reference drug benznidazol.

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Section: Other Activitiesmentioning

confidence: 89%

Section: Anti-inflammatory Activitymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Essential Oils from Annonaceae Species from Brazil: A Systematic Review of Their Phytochemistry, and Biological Activities

Cascaes

Carneiro

Nascimento

et al. 2021

IJMS

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“…Despite technological advances and the progress of medicine, 80% of the population of developing countries need traditional medicine for basic health care (Tomazzoni et al, 2006). Essential oils (EO) have several properties and their actions have been reported for the treatment of infections and inflammation (Ji et al, 2019;Ogunwande et al, 2019;Saldanha et al, 2019) and thrombosis (Ballabeni et al, 2007;Tognolini et al, 2007). However, few studies have been published about the effects of essential oils on the cardiovascular system (Asiful et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Chemical Profile Of Schinus molle L. Essential Oil And Its Antihemostatic Properties

Silveira

Guedes

Frattani

et al. 2020

Natural Volatiles and Essential Oils

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About 17.7 million people die each year from cardiovascular disorders and the essential oils have great importance in the development of research. The aim was to evaluate the chemical composition of the essential oil from Schinus molle (EOSM) and its antihemostatic activity. EOSM was obtained from leaves by hydrodistillation and characterized by GC-FID-MS. Anticoagulant assay was performed by activated Partial Thromboplastin Time (aPTT) and Prothrombin Time (PT) assays, and the platelet aggregation assays were performed using adenosine diphosphate (ADP) and collagen as inducers. Forty-one compounds were identified mainly sesquiterpenes (88.1%) of which epi-α-cadinol (22.8%) and γ-cadinene (9.7%) are the major compounds. EOSM did not show anticoagulant activity (40-400 mg/mL). EOSM oil was active against ADP inducer at 5 mg/mL (80%) and 40 mg/mL (48%), but against collagen the EOSM showed no activity. This is the first report on the antiplatelet action of Schinus molle.

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“…Essential (or volatile) oils have characteristic fragrances and these metabolites may be extracted by steam or hydrodistillation, resulting in complex mixtures of different classes of known or unknown compounds as hydrocarbons, terpene alcohols, aldehydes, ketones, phenols, and esters (Adeosun et al, 2013;Alves et al, 2015). Essential oils may include activities such as antimicrobial agent, antioxidant, anti-inflamatory, anti-proliferative (Kumar et al, 2019;Kurti et al, 2019), antifungal, antinociceptive (Lasram et al, 2019), anti-tumor (Saldanha et al, 2019) and pesticidal (Wei et al, 2019). In addition to these activities, volatile oils are also used in the manufacture of perfumes, aromatic soaps, scented lotions, and cosmetics (Adeosun et al, 2013).…”

mentioning

confidence: 99%

Essential oils of Cordia species, compounds and applications: a systematic review

Andrade¹,

Martins²,

Barros³

et al. 2022

BLACPMA

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The purpose of this systematic review was to identify the available literature on the essential oil from species of genus Cordia. This study followed the Preferred Reporting Items for Systematic Reviews. The search was conducted on four databases: LILACS, PubMed, Science Direct, and Scopus until June 5th, 2020, with no time or language restrictions. Sixty out of the 1,333 initially gathered studies fit the inclusion criteria after the selection process. Nine species of Cordiawere reported in the selected studies, out of which 79% of the evaluated studies reported essential oil from Cordia curassavica. The essential oil extraction methods identified were hydrodistillation and steam distillation. As for biological application, antimicrobial, anti-inflammatory, larvicidal and antioxidant activities were the most reported. The main compounds reported for essential oil were β-caryophyllene, α-humulene, α-pinene, bicyclogermacrene, and sabinene. The information reported in this systematic review can contribute scientifically to the recognition of the importance of the genus Cordia.

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Chemical composition and evaluation of the anti-inflammatory and antinociceptive activities of Duguetia furfuracea essential oil: Effect on edema, leukocyte recruitment, tumor necrosis factor alpha production, iNOS expression, and adenosinergic and opioidergic systems

Cited by 23 publications

References 76 publications

Essential Oils from Annonaceae Species from Brazil: A Systematic Review of Their Phytochemistry, and Biological Activities

Essential Oils from Annonaceae Species from Brazil: A Systematic Review of Their Phytochemistry, and Biological Activities

Chemical Profile Of Schinus molle L. Essential Oil And Its Antihemostatic Properties

Essential oils of Cordia species, compounds and applications: a systematic review

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