2013
DOI: 10.3109/13880209.2013.853810
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Chemical composition and evaluation of modulatory of the antibiotic activity from extract and essential oil of Myracrodruon urundeuva

Abstract: Context: The combination of antibiotics with natural products has demonstrated promising synergistic effects in several therapeutic studies. Objective: The aim of this study was to determine the effect of a combination of an ethanol extract of Myracrodruon urundeuva Fr. All. (Anacardiaceae) (aroeira plant) and its essential oil with six antimicrobial drugs against multiresistant strains of Staphylococcus aureus and Escherichia coli from clinical isolates. Materials and methods: After identification of the chem… Show more

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Cited by 24 publications
(19 citation statements)
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“…Many reports on the pharmacological properties of extracts and isolated compounds from M. urundeuva are found in the literature, corroborating its uses as antiulcer and gastroprotective (Carlini et al ), anti‐inflammatory and analgesic (Souza et al ), and antimicrobial against bacteria, fungi, and viruses (Sá et al ; Figueredo et al ; Cecilio et al ; Oliveira et al ). However, despite its large use in traditional herbal medicine, only a few reports on its toxicological effect can be found in the literature.…”
Section: Introductionmentioning
confidence: 80%
“…Many reports on the pharmacological properties of extracts and isolated compounds from M. urundeuva are found in the literature, corroborating its uses as antiulcer and gastroprotective (Carlini et al ), anti‐inflammatory and analgesic (Souza et al ), and antimicrobial against bacteria, fungi, and viruses (Sá et al ; Figueredo et al ; Cecilio et al ; Oliveira et al ). However, despite its large use in traditional herbal medicine, only a few reports on its toxicological effect can be found in the literature.…”
Section: Introductionmentioning
confidence: 80%
“…Several natural products have been investigated as to their modulatory properties, many of which present relevant synergistic effects, constituting an option in the fight against the phenomenon of microbial resistance . ‘Antibiotic activity modifiers’ is a term used to denote substances that modulate or even revert the bacterial resistance phenotype to certain antibiotics and may alter microbial susceptibility to antibiotics by inhibiting efflux pumps .…”
Section: Resultsmentioning
confidence: 99%
“…Uma estratégia que vem sendo utilizada visando atenuar este problema é a associação de fármacos com produtos naturais ou sintéticos que tenham a capacidade de suprimir os mecanismos de ê . βlactâmicos e produtos naturais tem apresentado resultados positivos (FIGUEREDO et al, 2013(FIGUEREDO et al, , 2014. A amoxicilina, ao ser associada a produtos naturais também teve seu efeito potencializado (CHAVES et al, 2018).…”
Section: Resultados E Discussõesunclassified