Chemical Composition andIn VitroAntioxidant, Cytotoxic, Antimicrobial, and Larvicidal Activities of the Essential Oil ofMentha piperitaL. (Lamiaceae)

Abstract

The essential oil was obtained by hydrodistillation and the identification and quantification of components were achieved with the use of GC-MS analysis. The antioxidant activity was evaluated by the method of sequestration of DPPH. Essential oils were used for study the cytotoxic front larvae of Artemia salina. In the evaluation of the antimicrobial activity of essential oils, we employed the disk-diffusion method. The potential larvicide in mosquito larvae of the third stage of development of Aedes aegypti to different concentrations of essential oils was evaluated. The major compounds found in the essential oils of M. piperita were linalool (51.8%) and epoxyocimene (19.3%). The percentage of antioxidant activity was 79.9 ± 1.6%. The essential oil showed LC50 = 414.6 μg/mL front of A. saline and is considered highly toxic. It shows sensitivity and halos significant inhibition against E. coli. The essential possessed partial larvicidal efficiency against A. aegypti.

The Hydroalcoholic Extract Obtained fromMentha piperitaL. Leaves Attenuates Oxidative Stress and Improves Survival in Lipopolysaccharide-Treated Macrophages

“…A similar result was observed for an aqueous extract from Mentha haplocalyx when incubated with LPS-stimulated macrophages [ 26 ]. These studies and others [ 12 , 17 , 24 ] also suggested an antioxidant potential for peppermint and other plants from the same genus. We found that H 2 O 2 , but not NO production, was decreased in LHAE-treated cells stimulated with LPS at concentrations as low as 1 μ g/ml.…”

“…M. piperita was previously suggested to have antimicrobial activity against both Gram-negative and Gram-positive bacteria [ 12 ], in addition to presenting with antioxidant potential in vitro [ 12 , 17 , 24 ]. In vivo anti-inflammatory actions were also reported for this plant in murine models of infection and inflammation.…”

“…Mentha piperita L., a member of the family Lamiaceae and popularly known as peppermint, is native to the Mediterranean region and has been spread worldwide due to its medicinal properties, taste, and aroma [ 11 ]. Its medicinal properties include antitumor, antimicrobial, and antioxidant actions and have been reported especially for its essential oil [ 12 – 17 ]. Of importance, M. piperita essential oil was previously shown to be effective against Gram-negative and Gram-positive bacteria and to act as a potential antioxidant in vitro [ 12 ].…”

“…Its medicinal properties include antitumor, antimicrobial, and antioxidant actions and have been reported especially for its essential oil [ 12 – 17 ]. Of importance, M. piperita essential oil was previously shown to be effective against Gram-negative and Gram-positive bacteria and to act as a potential antioxidant in vitro [ 12 ]. This essential oil was also shown to reduce the numbers of leukocytes in a murine model of skin inflammation [ 18 ] and modulate cytokine production in vivo [ 19 ].…”

Ethnomedicinal, phytochemical and pharmacological updates on Peppermint (Mentha × piperita L.)—A review

“…This study has demonstrated that 16.385 ± 0.24 μg/ml (Ascorbic acid equivalent anti‐oxidant capacity) and 47.23 ± .0.28% DPPH radical activity. Moreover, the anti‐oxidants activates of essential oil or extracts M. × piperita has been described some in the previous literatures (Benabdallah et al, ; da Silva Ramos et al, ; Goudjil et al, ; Kratchanova et al, ; Pramila et al, ; Zheng & Wang, ). Anti‐oxidant activities are depicted in Table .…”