Chemical composition and in vitro aryl hydrocarbon receptor-mediated activity of atmospheric particulate matter at an urban, agricultural and industrial site in North Africa (Bizerte, Tunisia)

Barhoumi, Badreddine; Tedetti, Marc; Onrubia, Javier A. Tesán; Dufour, Aurélie; Doan, Thi-Que; Boutaleb, Samiha; Touil, Soufiane; Scippo, Marie‐Louise

doi:10.1016/j.chemosphere.2020.127312

Cited by 9 publications

(4 citation statements)

References 106 publications

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“…PM 10 samples collected between January 2015 and February 2016 at an urban site at Zouaghi, in the south of Constantine, showed that PM concentrations exceeded the WHO’s 24-h guideline value (50 µg m −3 ), linking such levels to resuspended dust and Saharan dust [ 64 ]. In Tunisia, the analysis of PM 10 constituents revealed the anthropogenic and natural sources of PM, derived from traffic emissions, heavy industries, biomass burning, mechanic and electronic factories, and agricultural activities gathered with meteorological conditions [ 65 ]. In Egypt, a study in the residential-industrial area Shubra El-Kheima in the north of Greater Cairo revealed that fine aerosol particle concentrations, collected during the period from October 2010 to May 2011, exceed the WHO annual Air Quality Standard levels.…”

Section: Resultsmentioning

confidence: 99%

A Review on Climate, Air Pollution, and Health in North Africa

Sekmoudi¹,

Bouakline

Khomsi

et al. 2022

Curr Envir Health Rpt

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Purpose of Review The aim of this review is to summarize and provide clear insights into studies that evaluate the interaction between air pollution, climate, and health in North Africa. Recent Findings Few studies have estimated the effects of climate and air pollution on health in North Africa. Most of the studies highlighted the evidence of the link between climate and air pollution as driving factors and increased mortality and morbidity as health outcomes. Each North African country prioritized research on a specific health factor. It was observed that the health outcome from each driving factor depends on the studied area and data availability. The latter is a major challenge in the region. As such, more studies should be led in the future to cover more areas in North Africa and when more data are available. Data availability will help to explore the applicability of different tools and techniques new to the region. Summary This review explores studies related to climate and air pollution, and their possible impacts on health in North Africa. On one hand, air quality studies have focused mainly on particulate matter exceedance levels and their long-term exposure impacts, namely, morbidity and mortality. The observed differences between the various studies are mainly due to the used exposure–response function, the studied population, background emissions, and natural emission from the Sahara Desert that characterize the region. On the other hand, climate studies have focused primarily on the impact of heat waves, vector-borne disease, and mental disorders. More than half of these studies have been on leishmaniasis disease. The review revealed unbalanced and insufficient research on health impacts from air pollution episodes and climate extremes across the region.

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Section: Resultsmentioning

confidence: 99%

A Review on Climate, Air Pollution, and Health in North Africa

Sekmoudi¹,

Bouakline

Khomsi

et al. 2022

Curr Envir Health Rpt

View full text Add to dashboard Cite

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“…In this study, the concentration of 16 US EPA priority PAHs in PM 2.5 of Xi'an between November 15 and December 23, 2019 (the heating season), were analyzed. It was worth noting that the Acenaphthene (Ace) concentration in Xi'an was significantly higher than that in South Korea, Thailand, or the United States and even higher than that in other regions of China (Baek et al, 2020; Barhoumi et al, 2020; Dejchanchaiwong et al, 2020; Han et al, 2019; Khadhar et al, 2010). However, the other 15 kinds of PAHs have no significant difference as compared with these in other regions in China.…”

Section: Discussionmentioning

confidence: 99%

Cytotoxicity and inflammatory effects in human bronchial epithelial cells induced by polycyclic aromatic hydrocarbons mixture

Wang

Liu²,

Qing-bo³

et al. 2021

J of Applied Toxicology

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Polycyclic aromatic hydrocarbons (PAHs) are the most common contaminants in the air pollutants. Inhalation exposure to PAHs could increase the risk of respiratory disease, cardiovascular disease and even cancer. However, the biotoxicity of multi‐component PAHs from atmospheric pollutants has been poorly studies. The main topic of this study was to investigate the PAHs mixture, which derived from atmospheric pollutants, induced toxic effects and inflammatory effects on human bronchial epithelial cells in vitro. The results showed that PAHs mixture could decrease the cell viability, increase the apoptosis rate, and induce cell cycle arrest at S‐phase. Furthermore, the expression of inflammatory factors IL‐1β and IL‐6 were increased and NF‐κB signaling pathway was activated in PAHs mixture‐treated cells. The findings of this study indicate that PAHs mixture‐induced cytotoxicity and inflammation may be related to intracellular ROS generation and to the activated NF‐κB signaling pathway.

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“…However, the same fate can happen in MPs suspended in the atmosphere. Indeed, some POPs formed during the combustion process, such as polychlorinated dibenzodioxin and dibenzofurans, have been already detected in atmospheric PM [139]. In the atmosphere, MPs could be exposed to POPs but the adsorption is dependent on the time at which plastic particles are suspended.…”

Section: Contaminants Associated With Mp-npsmentioning

confidence: 99%

Newly Emerging Airborne Pollutants: Current Knowledge of Health Impact of Micro and Nanoplastics

Facciolà

Visalli

Ciarello

et al. 2021

IJERPH

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Plastics are ubiquitous persistent pollutants, forming the most representative material of the Anthropocene. In the environment, they undergo wear and tear (i.e., mechanical fragmentation, and slow photo and thermo-oxidative degradation) forming secondary microplastics (MPs). Further fragmentation of primary and secondary MPs results in nanoplastics (NPs). To assess potential health damage due to human exposure to airborne MPs and NPs, we summarize the evidence collected to date that, however, has almost completely focused on monitoring and the effects of airborne MPs. Only in vivo and in vitro studies have assessed the toxicity of NPs, and a standardized method for their analysis in environmental matrices is still missing. The main sources of indoor and outdoor exposure to these pollutants include synthetic textile fibers, rubber tires, upholstery and household furniture, and landfills. Although both MPs and NPs can reach the alveolar surface, the latter can pass into the bloodstream, overcoming the pulmonary epithelial barrier. Despite the low reactivity, the number of surface area atoms per unit mass is high in MPs and NPs, greatly enhancing the surface area for chemical reactions with bodily fluids and tissue in direct contact. This is proven in polyvinyl chloride (PVC) and flock workers, who are prone to persistent inflammatory stimulation, leading to pulmonary fibrosis or even carcinogenesis.

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Chemical composition and in vitro aryl hydrocarbon receptor-mediated activity of atmospheric particulate matter at an urban, agricultural and industrial site in North Africa (Bizerte, Tunisia)

Cited by 9 publications

References 106 publications

A Review on Climate, Air Pollution, and Health in North Africa

A Review on Climate, Air Pollution, and Health in North Africa

Cytotoxicity and inflammatory effects in human bronchial epithelial cells induced by polycyclic aromatic hydrocarbons mixture

Newly Emerging Airborne Pollutants: Current Knowledge of Health Impact of Micro and Nanoplastics

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