Chemical composition and toxicological evaluation of Hyptis suaveolens (L.) Poiteau (LAMIACEAE) in Drosophila melanogaster and Artemia salina

Bezerra, José Weverton Almeida; Costa, Adrielle Rodrigues; Silva, M.A.P. da; Rocha, Maria Ivaneide; Boligon, Alexandra Augusti; Rocha, João Batista Teixeira da; Barros, Luiz Marivando; Kamdem, Jean Paul

doi:10.1016/j.sajb.2017.10.003

Cited by 69 publications

(61 citation statements)

References 25 publications

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“…In addition, Rocha et al [19] states that the constituent in higher percentage is the α-cadinol, reaching compose 19% of the total composition, and in our study this sesquiterpeno is in low percentages (4.2%). This variation is justified by several factors, both intrinsic and genetic, as well as extrinsic factors such as geographic origin of the plant, cultivation, collection form, and especially the period of the year that was collected [20][21][22].…”

Section: Discussionmentioning

confidence: 99%

Antibiotic Potential and Chemical Composition of the Essential Oil of Piper caldense C. DC. (Piperaceae)

et al. 2020

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Infections by multiresistant microorganisms have led to a continuous investigation of substances acting as modifiers of this resistance. By following this approach, the chemical composition of the essential oil from Piper caldense leaf and its antimicrobial potential were investigated. The antimicrobial activity was determined by broth microdilution method providing values for minimum inhibitory concentration (MIC), IC50, and minimum fungicidal concentration (MFC). The essential oil was tested as a modulator for several antibiotics, and its effect on the morphology of Candida albicans (CA) strains was also investigated. The chemical characterization revealed an oil composed mainly of sesquiterpenes. Among them are caryophyllene oxide (13.9%), spathulenol (9.1%), δ-cadinene (7.6%) and bicyclogermacrene (6.7%) with the highest concentrations. The essential oil showed very low activity against the strains of CA with the lowest values for IC50 and MFC of 1790 μg/mL and 8192 μg/mL, respectively. The essential oil modulated the activity of fluconazole against CA URM 4387 strain, which was demonstrated by the lower IC50 obtained, 2.7 μg/mL, whereas fluconazole itself presented an IC50 of 7.76 μg/mL. No modulating effect was observed in the MFC bioassays. The effect on fungal morphology was observed for both CA INCQS 40006 and URM 4387 strains. The hyphae projection was completely inhibited at 4096 μg/mL and 2048 μg/mL, respectively. Thus, the oil has potential as an adjuvant in antimicrobial formulations.

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Section: Discussionmentioning

confidence: 99%

Antibiotic Potential and Chemical Composition of the Essential Oil of Piper caldense C. DC. (Piperaceae)

et al. 2020

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“…The essential oils obtained were first diluted in Dimethyl sulfoxide (DMSO) at a 1% DMSO percentage to avoid interference with germination, and were subsequently diluted to the 1000, 500, 250 and 125 μg/mL concentrations for the realization of the allelopathic bioassays. The concentrations used in this study are based on the fact that the species present variations in the leaf drop rates, and that M. suaveolens is the one with the greatest contribution in leaf dry biomass in relation to the other aromatic species, with a rate of 3 sheets tonelas per hectare, and as its oil has a yield of 0.153% dry weight yield, will have a ratio of around 459 µg of oil per ml of soil, whereas the leaves are in an engagement with depth of 1 cm from soil (Bezerra et al, 2017).…”

Section: Allelopathic Activity Of the Essential Oilsmentioning

confidence: 99%

“…Therefore, there is an increase in the production and release of secondary metabolites, especially volatile terpenes (Oliveira Junior et al, 2011). Thus, allelochemical release in the medium will be greater at times of prolonged drought and high temperatures for L. montevidensis, L. camara and T. spinosa, since these species present leaves during the dry season, while M. suaveolens is not established in this period as it is an annual species which grows and reproduces during the rainy season (Bezerra et al, 2017).…”

Section: Jamacaru D D Deviationmentioning

confidence: 99%

Allelopathy of Aromatic Species on the Germination of Cereus jamacaru DC. subsp. jamacaru (Cactaceae)

Bezerra¹,

Santos²,

Meiado³

et al. 2018

JAS

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Cereus jamacaru DC subsp. jamacaru, has been suffering from severe anthropic pressure, in addition, when their seeds are dispersed, some end up not germinating due to the action of allelochemicals. Therefore, the present study was to evaluate the allelopathic effect of the essential oil (EO) from four species over C. jamacaru germination, as well as to identify their constituents. Four plants were selected for EO extraction (Mesospherum suaveolens (L.) Kuntze, Lantana montevidensis (Spreng.) Briq., Lantana camara L., and Tarenaya spinosa (Jacq.) Raf.) and the chemical analysis was performed by GC-MS. In order to evaluate the allelopathic activity of the EO's, the C. jamacaru seeds were treated with the EO's. The results showed that the EO's presented heterogeneity in their composition, with M. suaveolens presenting the highest number of constituents (44), followed by L. camara (26), T. spinosa (23) and L. montevidensis (22). All the oils negatively affected the C. jamacaru germination percentage in a concentration-dependent manner. Regarding the GVI, the M. suaveolens, L. montevidensis and L. camara OEs significantly decreased this index at all analyzed concentrations. Based on the results obtained, it is suggested that C. jamacaru should not be sown close to the aforementioned aromatic species in reforestation programs.

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“…Hiệu suất thu tinh dầu có thể thay đổi tùy thuộc vào các yếu tố như khí hậu, loại đất, và thời gian thu hoạch 10 . Hiệu suất thu tinh dầu lá tía tô dại ở Australia là 0,1% và ở Brazil là 0,153%, nhưng ở Nigeria là 1,5% và ở Nghệ An là 0,22% [11][12][13][14] . Tinh dầu từ lá tươi cỏ lào ở Benin (Tây Phi) có hiệu suất là 0,1% và ở Kerala (Ấn Độ) là 0,2% 15,16 .…”

Section: Kết Quả Và Thảo Luận Hiệu Suất Thu Tinh Dầuunclassified

Antifeedant and larvicidal activities of leaf essential oils from Hyptis suaveolens (L.) Poit., Chromolaena odorata (L.) R.M. King and Lantana camara L. against Spodoptera litura Fab. (Lepidoptera: Noctuidae)

Tran

Luong

Lệ

et al. 2020

Sci. Tech. Dev. J. - Nat. Sci.

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The current study was carried out to evaluate antifeedant and insecticidal activities of three essential oils from leaves of Hyptis suaveolens, Chromolaena odorata and Lantana camara against fourth instar larvae of Spodoptera litura under the laboratory conditions. Results indicated that the essential oil from leaves of Hyptis suaveolens had a strong antifeedant impact on the larvae with antifeedant index (AI) of 75.4, 88.5 and 92.9 when leaf disks of Ipomoea batatas were treated with the essential oil at concentration of 1.5, 2.0 and 2.5 %, respectively. Also dose dependent mortalities were observed in the larvae topical treated with the essential oil at different concentrations. At the treated concentration of 0.4 mg per each larva, 68.3 % of the larvae were killed after 24 hours, and 25.0 % were died at the pupal stage after 30 days of observation. At the concentration of 1.2 mg/larva, 93.3 % of the larvae were killed after 24 hours, and no emergence of adults was recorded after 30 days of observation. Larvicidal activity of the H. suaveolens essential oil (with the lethal doses LD50=0.16 and LD95=1.52 mg/larva) was stronger than those of the C. odorata and L. camara essential oils (with LD50=0.57–0.63 and LD95=4.64–4.97 mg/larva) after 24 hour of treatment. GC–MS analysis indicates that the major volatile components of the essential oil from leaves of H. suaveolens are composed of b-caryophyllene (30.0 %), eucalyptol (12.0 %), copaene (5.9 %), and a-bergamotene (5.7 %). This essential oil needs to be further investigated and used as a bio-insecticide for control of S. litura.

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Chemical composition and toxicological evaluation of Hyptis suaveolens (L.) Poiteau (LAMIACEAE) in Drosophila melanogaster and Artemia salina

Cited by 69 publications

References 25 publications

Antibiotic Potential and Chemical Composition of the Essential Oil of Piper caldense C. DC. (Piperaceae)

Antibiotic Potential and Chemical Composition of the Essential Oil of Piper caldense C. DC. (Piperaceae)

Allelopathy of Aromatic Species on the Germination of Cereus jamacaru DC. subsp. jamacaru (Cactaceae)

Antifeedant and larvicidal activities of leaf essential oils from Hyptis suaveolens (L.) Poit., Chromolaena odorata (L.) R.M. King and Lantana camara L. against Spodoptera litura Fab. (Lepidoptera: Noctuidae)

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