Chemical Composition, Antioxidant Activity and Cytotoxicity of Essential Oil of Mentha viridis

Hassan, Hiba A; Kabbashi, Ahmed S.; Abedallah, Ali; Wagh, Vitthal D.; Hamdi, Omer Abdalla Ahmed

doi:10.31080/asms.2019.03.0368

Cited by 1 publication

(1 citation statement)

References 11 publications

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“…Moreover, it is widely known as a strong stimulant and carminative 14 . M. viridis extract contains various terpenes, fatty acid esters and Vitamin E, which explains its antioxidant potential 15 . The essential oil from leaves of M. viridis has potent antimicrobial activity 16 .…”

Section: Introductionmentioning

confidence: 99%

Chemical Composition, Antimicrobial Activity and Potential Cytotoxic Effect of Mentha Viridis (Spearmint) Extracts from Saudi Arabia

Ali

2021

Orient. J. Chem

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Many medicinal plants have been used to treat and prevent illnesses in Saudi Arabia. The present study aimed to investigate the chemical composition of Mentha viridis obtainedfrom Albaha region of Saudi Arabiaand evaluate its antimicrobial and antiproliferative potential. The extract was obtained from plant fresh material and identified by gas chromatography-mass spectrometry (GC-MS). The antimicrobial and antiproliferative potential of the plant extract was analysed by performing four subsequent extracts: ethanol, petroleum ether, chloroform, and methanol. The GC-MS analysis showed carvone as a main component, as it comprised 64.82 % of the plant extract. In antimicrobial activity, methanol extract showed significant activityagainst Pseudomonas aeruginosa with zone of inhibition of 15 mm. The MTT assay showed thatpetroleum ether and chloroform extracts have moderate cytotoxic effect against MCF-7 breast cancer cell line with IC50 values of 193.23 μg/mL and 131.86 μg/mL, respectively. Chloroform extract also showed mild activity against HCT-116 colorectal cancer cell line with IC50value of 189.2 μg/mL. This study highlights the potential of M. viridis extracts as powerful bioactive phytochemicals with possible role in diseases and cancer therapy.

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Section: Introductionmentioning

confidence: 99%

Chemical Composition, Antimicrobial Activity and Potential Cytotoxic Effect of Mentha Viridis (Spearmint) Extracts from Saudi Arabia

Ali

2021

Orient. J. Chem

View full text Add to dashboard Cite

show abstract

Chemical Composition, Antioxidant Activity and Cytotoxicity of Essential Oil of Mentha viridis

Cited by 1 publication

References 11 publications

Chemical Composition, Antimicrobial Activity and Potential Cytotoxic Effect of Mentha Viridis (Spearmint) Extracts from Saudi Arabia

Chemical Composition, Antimicrobial Activity and Potential Cytotoxic Effect of Mentha Viridis (Spearmint) Extracts from Saudi Arabia

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