Chemical composition, antioxidant and antibacterial activity of Adiantum capillus-veneris L. extract from Algeria

Abstract

The present study evaluates the antioxidant and antibacterial activities as well as the chemical composition of the aerial part of Adiantum capillus-veneris L., which are endemic to the flora of Algeria. The total phenolic amount of the hydromethanolic extract, as measured by the Folin-Ciocalteu reagent procedure, was found to be about 23.44 ± 0.14 mg GAE/g DW, while the flavonoid content value was 4.66 ± 0.01 mg CE/g DW, as measured by aluminum chloride colorimetric method. The antioxidant power of the extract was analyzed using the DPPH method. DPPH radicals were scavenged with an IC50 value of 65.85 µg/mL. The antibacterial activity of hydromethanolic extract against five bacterial strains of Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 25853), Staphylococcus aureus (ATCC 25923), Streptococcus pneumoniae and Bacillus cereus (ATCC 10876) were carried out using the disc diffusion test and the microdilution method. Streptococcus pneumoniae is the most sensitive bacterium with inhibition zone of 9.0 ± 1.1 cm and MIC=10 mg/mL. Based on HPLC analysis, we find that quercetin 3-O-glucoside was the most abundant compound in the plant extract. This study demonstrates that Adiantum capillus-veneris could be a potential natural source of antibacterial and antioxidant compounds.

Mitigation of Hepatotoxicity via Boosting Antioxidants and Reducing Oxidative Stress and Inflammation in Carbendazim-Treated Rats Using Adiantum Capillus-Veneris L. Extract

“…Based on the previously published LC-MS, HPLC, and phytochemical results, which indicated the presence of compounds terpenes, flavonoids, phenolics, and sulfated compounds [ 19 , 20 , 21 , 22 , 23 , 29 ] in the ACVL extract, in the current study, we only focused on the non-polar profile of the extract that had not been completely investigated before.…”

“…In brief, previous phytochemical reports have demonstrated the existence of different carotenoids such as pheophytin derivatives, carotene epoxide, xanthin derivatives, neochrome, lutein, chlorophyll a, and b; terpenes such as isoadiantone, isoadiantol-B, 3-methoxy-4-hydroxyfilican,e and 3,4 dihydroxyfilicane; phenolic acid derivatives such as 4-hydroxybenzoic acid, O -caffeoylquinic acid, 2-caffeoyl tartaric acid, p-Coumaric acid, rosmarinic acid, gentisic acid, coumaric acid derivative, and ferulic acid; flavonoids and their derivatives, such as kaemferol-3-feruloylsophoroside-7-glucoside, quercetin hexoside, caffeic acid hexoside, kaempferol-3- O -sophorotrioside, quercetin rhamnoside-hexoside, quercetin-3-galactoside, apigenin-7- O -glucoside, isorhamnetin-3- O -di-glucoside, epicatechin 7- O -rutinoside, and kaempferol 3- O -glucoside; quercetin-3- O -glucoside, quercetin-3- O -rutinoside (rutin), and Kaempferol 3-sulphat [ 19 , 20 , 21 , 22 , 23 ]; and sulphate esters of hydroxycinnamic acid sugars [ 19 ].…”

Adiantum capillus-veneris and Respiratory Diseases

“…Studies have shown that Pare-siavashan is a natural source of antimicrobial compounds. 39 The antimicrobial and some other effects of Paresiavashan are presented in Table 3 in detail.…”

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“…The plant is widespread in regions with warm or tropical temperatures with high humidity(Kashkooe et al, 2021). Therefore, it could be found in different areas in southern Europe, the Atlantic coast of Ireland, and northern Africa(Boukada et al, 2022). Typical habitats are limestone cliffs away from direct insolation (Al-Snafi, 2015).…”

“…capillus-veneris is characterized by a long history of medicinal use. The medicinal parts of the plant are the leafy fronds, rhizomes, and roots(Boukada et al, 2022). The fresh and dried leaves are used as antidandruff, antitussive, astringent, demulcent, depurative, diuretic, emetic, emmenagogue, emollient, expectorant, galactagogue, laxative, pectoral, refrigerant, stimulant, sudorific and tonic.…”