Chemical composition of essential oil of the Litsea cambodiana Lecomte and Litsea salmonea A. Chev. from Bach Ma national park

Son, Le C.; Huyen, Duong Duc; Thăng, Trân Đình; Đài, Đỗ Ngọc

doi:10.15625/0866-7160/v35n3.3380

Cited by 1 publication

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“…Surprisingly, the abundance carvacrol (20.8%), cis - β -guaiene (6.4%) and khusimone (3.9%) presented in L balansae essential oil were conspicuously absent in all of the other oil samples. 15,16,17,18 The differences observed in the chemical classes and composition of Litsea essential oils can be attributed to a range of factors. These include the nature of the plant, its geographical location, the methods used for extraction, the specific parts of the plant utilized, the conditions under which it was cultivated, and the stage of maturity at which it was harvested.…”

Section: Resultsmentioning

confidence: 99%

GC-MS Characterization, in Vitro Antioxidant and Anti-Inflammatory Activities of Essential oil from the Leaves of Litsea balansae Lecomte

Ho,

Hoang,

Nguyen

et al. 2023

Natural Product Communications

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Objective: This study aimed to analyze the essential oil obtained from Litsea balansae Lecomte leaves and investigate its potential as an anti-inflammatory and antioxidant agent. Methods: Fresh L balansae leaves were collected in Quangtri, Vietnam, and subjected to hydro-distillation using a Clevenger-type apparatus to extract the essential oil. The essential oil composition was analyzed using gas chromatography–mass spectrometry (GC-MS). Antioxidant capacity was evaluated through the 2,2-Diphenyl-1-picrylhydrazyl assay, while the inhibition of nitric oxide production was assessed in lipopolysaccharide-activated RAW264.7 cells. Results: GC-MS analysis identified 71 compounds, constituting 99.3% of the essential oil. Key constituents included carvacrol (20.8%), caryophyllene oxide (11.0%), cis-β-guaiene (6.4%), khusimone (3.9%), bicycloelemene (3.7%), and spathulenol (3.7%). The essential oil exhibited a moderate antioxidant effect (half maximal inhibitory concentration [IC50] = 208.37 ± 10.67 µg/mL) and significant anti-inflammatory activity (IC50 = 28.09 ± 1.53 µg/mL). Conclusion: The essential oil derived from L balansae leaves showcases potential as an anti-inflammatory and antioxidant agent, as indicated by its chemical composition and biological activities. These findings suggest promising avenues for further research in the development of therapeutic agents from natural sources.

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