Chemical composition of hexane and chloroform extracts from Artemisia scopaeformis

Bopi, A. K.; Kudaibergen, A.A.; Dyusebaeva, Moldyr; Feng, Yunjiang; Jenis, Janar

doi:10.26577/ijbch-2019-i2-16

Cited by 2 publications

(4 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The plant extract was further investigated for fatty and amino acid compositions. The most dominant fatty acid in A. scopaeformis was unsaturated fatty acidlinoleic acid, which, along with glutamate, is one of the most abundant in amino acids [89]. Crude extract was obtained from the aerial part of A. scopaeformis through selective sequential extraction with solvents of increasing polarity, namely, n-hexane and chloroform.…”

Section: Traditional Use Phytochemical Profiles and Pharmacological P...mentioning

confidence: 99%

“…Crude extract was obtained from the aerial part of A. scopaeformis through selective sequential extraction with solvents of increasing polarity, namely, n-hexane and chloroform. GC-MS analysis of the n-hexane and chloroform extracts revealed the presence of various bioactive compounds which can be responsible for antioxidant, antifungal, antimicrobial, anti-inflammatory and anticancer potentials [90].…”

Section: Traditional Use Phytochemical Profiles and Pharmacological P...mentioning

confidence: 99%

“…A. frigida contains 1,8cineole (24.7%), camphor (22.6%) and borneol (8.9%), where thujone (5.2%) and thujanols (1.3-2.5%) were distinguished quantitatively [80]. A. scopaeformis hexane extract contains four main compounds: methyleugenol (33.87%), hexadecanoic acid, ethyl ester (41.02%), butyl 4,7,10,13,16,19-docosahexaenoate (11.55%) and hexasiloxane (13.56%) [89,90]. The chloroform extract of A. scopaeformis contains five major compounds: fluorene, 2,7-bis (1-hydroxyethyl 24.28%), p-imethylaminobenzylidene p-anisidine (14.59%), 3-acetoxy-5methyl-2-nitro-terephthalic acid, 4-isopropyl ester 1-methyl ester (11.74%), 3,4-diacetyl-2-methyl-4H-thieno [3,2-b] pyrrole-5-carboxylic acid, methyl ester (17.35%) and 4H-1,2,4triazole-3-thiol, 4-2-fluorophenyl)-5-(1-methylethyl) (32.04%) [89,100].…”

Section: Essential Oil Contents Of Artemisia Species From Central Asiamentioning

confidence: 99%

“…Major components of essential oils from Artemisia species of Central Asia[6,67,69,70,74,75,80,81,86,89,90,[99][100][101][102][103].…”

mentioning

confidence: 99%

See 3 more Smart Citations

Traditional Use, Phytochemical Profiles and Pharmacological Properties of Artemisia Genus from Central Asia

et al. 2022

Self Cite

View full text Add to dashboard Cite

The flora of Kazakhstan is characterized by its wide variety of different types of medicinal plants, many of which can be used on an industrial scale. The Traditional Kazakh Medicine (TKM) was developed during centuries based on the six elements of ancient Kazakh theory, associating different fields such as pharmacology, anatomy, pathology, immunology and food nursing as well as disease prevention. The endemic Artemisia L. species are potential sources of unique and new natural products and new chemical structures, displaying diverse bioactivities and leading to the development of safe and effective phytomedicines against prevailing diseases in Kazakhstan and the Central Asia region. This review provides an overview of Artemisia species from Central Asia, particularly traditional uses in folk medicine and the recent numerous phytochemical and pharmacological studies. The review is done by the methods of literature searches in well-known scientific websites (Scifinder and Pubmed) and data collection in university libraries. Furthermore, our aim is to search for promising and potentially active Artemisia species candidates, encouraging us to analyze Protein Tyrosine Phosphatase 1B (PTP1B), α-glucosidase and bacterial neuraminidase (BNA) inhibition as well as the antioxidant potentials of Artemisia plant extracts, in which endemic species have not been explored for their secondary metabolites and biological activities so far. The main result of the study was that, for the first time, the species Artemisia scopiformis Ledeb. Artemisia albicerata Krasch., Artemisia transiliensis Poljakov, Artemisia schrenkiana Ledeb., Artemisia nitrosa Weber and Artemisia albida Willd. ex Ledeb. due to their special metabolites, showed a high potential for α-glucosidase, PTP1B and BNA inhibition, which is associated with diabetes, obesity and bacterial infections. In addition, we revealed that the methanol extracts of Artemisia were a potent source of polyphenolic compounds. The total polyphenolic contents of Artemisia extracts were correlated with antioxidant potential and varied according to plant origin, the solvent of extraction and the analytical method used. Consequently, oxidative stress caused by reactive oxygen species (ROS) may be managed by the dietary intake of current Artemisia species. The antioxidant potentials of the species A. schrenkiana, A. scopaeformis, A. transiliensis and Artemisia scoparia Waldst. & Kitam. were also promising. In conclusion, the examination of details between different Artemisia species in our research has shown that plant materials are good as an antioxidant and eznyme inhibitory functional natural source.

show abstract

Section: Traditional Use Phytochemical Profiles and Pharmacological P...mentioning

confidence: 99%

Section: Traditional Use Phytochemical Profiles and Pharmacological P...mentioning

confidence: 99%

Section: Essential Oil Contents Of Artemisia Species From Central Asiamentioning

confidence: 99%

“…Major components of essential oils from Artemisia species of Central Asia[6,67,69,70,74,75,80,81,86,89,90,[99][100][101][102][103].…”

mentioning

confidence: 99%

See 2 more Smart Citations

Traditional Use, Phytochemical Profiles and Pharmacological Properties of Artemisia Genus from Central Asia

et al. 2022

Self Cite

View full text Add to dashboard Cite

show abstract

Molecular docking analysis of Salvia sclarea flower extracts evaluated for protein target affinity based on different extraction methods

Torunoglu,

Aytar,

Durmaz

2024

Food Science & Nutrition

View full text Add to dashboard Cite

This study evaluates the antioxidant activity and total phenolic, flavonoid, flavonol, and tannin contents of extracts obtained from the flower parts of Salvia sclarea using different extraction methods, such as maceration and rotavapor (RE). The results indicate that the maceration method yields extracts with higher antioxidant activity compared to the rotavapor method (DPPH IC50: 260.70 ± 65.41 mg/mL vs. 345.48 ± 27.91 mg/mL). Additionally, the maceration method produces higher values in terms of total phenolic (26.4 ± 7.78 mg GAE/g extract), flavonoid (10.44 ± 0.21 mg QE/g extract), flavonol (9.20 ± 0.84 mg QE/g extract), and tannin contents (8.36 ± 0.39 mg GAE/g extract), whereas the RE method shows lower values (phenolics: 19.8 ± 3.31 mg GAE/g extract, flavonoids: 10.35 ± 0.35 mg QE/g extract, flavanol's: 5.45 ± 0.01 mg QE/g extract, and tannins: 7.72 ± 0.10 mg GAE/g extract). The gas chromatography–mass spectrometry (GC–MS) analysis of the extracts identified various bioactive compounds. Molecular docking studies revealed that Terpinen‐4‐ol obtained through maceration exhibits a strong binding affinity to a specific protein target, indicating potential biological activity. The predicted pharmacokinetic (ADME (absorption, distribution, metabolism, and excretion)) parameters for Terpinen‐4‐ol suggest favorable absorption and central nervous system (CNS) penetration, while Squalene obtained through maceration shows different pharmacokinetic properties. S. sclarea highlights significant antioxidant potential and provides insight into the bioactive compounds obtained through different extraction methods. To further investigate the potential biological interactions arising from these differences, molecular docking studies were conducted.

show abstract

Chemical composition of hexane and chloroform extracts from Artemisia scopaeformis

Cited by 2 publications

References 8 publications

Traditional Use, Phytochemical Profiles and Pharmacological Properties of Artemisia Genus from Central Asia

Traditional Use, Phytochemical Profiles and Pharmacological Properties of Artemisia Genus from Central Asia

Molecular docking analysis of Salvia sclarea flower extracts evaluated for protein target affinity based on different extraction methods

Contact Info

Product

Resources

About