Chemical constituents and evaluation of cytotoxic and antifungal activity of Lantana camara essential oils

Medeiros, Lídia B. P.; Rocha, Márcio dos Santos; Lima, Sidney Gonçalo de; Júnior, Gustavo R. de Sousa; Citó, Antônia Maria das Graças Lopes; Silva, Davi da; Lopes, José Arimateia Dantas; Moura, Dinara Jaqueline; Saffi, Jenifer; Mobin, Mitra; Costa, José Galberto Martins da

doi:10.1590/s0102-695x2012005000098

Cited by 24 publications

(17 citation statements)

References 47 publications

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“…Antifungal activity of EOLC leaves was studied against C. albicans and C. krusei ATCC 6258. The EO remarkably inhibited the growth of the fungi tested [107]. The EO of L. camara flowers exhibited antifungal activity against C. albicans and C. glabrata in all the concentrations tested [69].…”

Section: Eosmentioning

confidence: 92%

Antimicrobial Activities of Lantana Camara Linn.

Girish¹

2017

Asian J Pharm Clin Res

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Herbal drugs are the potential sources of therapeutic aid for the treatment and prevention of number of ailments as recognized very early by Ayurveda, Unani, and traditional folk -medical practitioners. The rich biodiversity of plants makes them a treasure house for obtaining new and novel compounds either themselves as drugs or lead molecules for drugs with different mechanisms of action. Lantana camara L. belonging to the family Verbenaceae and universally known as wild or red sage is the most widespread species of the genus. It occurs in most parts of the world as an evergreen notorious weed species. It is also considered as an ornamental garden plant. It is widely used in different traditional medical practices for treating various health problems. Different parts of the plant are used in treating various human ailments. The plant extracts and essential oil of L. camara possess various bioactivities including antimicrobial activities. The therapeutic potential of the plant is due to the occurrence of many bioactive phytocompounds. In last decade, scientists and researchers around the globe have elaborately studied the chemical composition of the whole plant of L. camara as well as its biological activities. This article reviews the antimicrobial activities of L. camara.

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Section: Eosmentioning

confidence: 92%

Antimicrobial Activities of Lantana Camara Linn.

Girish¹

2017

Asian J Pharm Clin Res

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“…The voucher specimen was collected by Dr. Sidney Lima, and identified by Dr. Roseli Farias Melo Barros (UFPI), and deposited in the Herbarium Graziela Barroso the Federal University of Piauí,Brazil,(number 27.273) EXTRACTION AND ANALYSIS Samples of fresh leaves and stems (about 300 g) of C. zehntneri was subjected to hydrodistillation (4h) to obtain the essential oil, and classic column chromatography technique was used as purification of the estragole. The essential oil and pure estragole was analyzed by Shimadzu GC-17A/MS QP5050A-GC-MS system according to Medeiros et al (2012). The identity of each compound was determined by comparison of its retention index relative to C 8 -C 20 n-alkanes (Fluka Analytical, 1.0 mL Alkane Standard Solution), as well as by its spectra with the database library Wiley 229.…”

Section: Plant Materialsmentioning

confidence: 99%

Isolation, characterization and evaluation of antimicrobial and cytotoxic activity of estragole, obtained from the essential oil of croton zehntneri (euphorbiaceae)

Andrade

Lima

Freitas

et al. 2015

An. Acad. Bras. Ciênc.

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Croton zehntneri (Euphorbiaceae) is a native aromatic plant from Northeast region of Brazil. The monoterpenoid estragole (ESL) has been isolated by classical chromatographic methods from the essential oil (EO) of C. zehnteneri leaves and characterized by GC-FID and GC-MS, its antimicrobial and cytotoxic potentials being assessed. The analysis of the EO enabled the identification of 100% of the integrated constituents, of which yield was about 1.8%. The main components identified were: eucalyptol, estragole (84.7%) and spathulenol. The dosage of 50 μg/disk of ESL presented fairly significant zones of inhibition against Gram-positive bacteria and fungi. The ESL presented toxicity against Artemia salina with LC 50 and LC 90 of 4,54 and 8,47 μg mL -1 . However, in tumor inhibition assays (human cells), there were no rewarding inhibition in any of the human cancer cell lines (MCF-7, HEP-2 and NCI-H292).

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“…Different solvent extracts produced from L. camara have already been studied, showing the occurrence of flavonoids, triterpenes, and glycosides [5]. These extracts and compounds were described as having interesting antioxidant, anti-inflammatory [11][12][13], antibacterial, cytotoxic, antifungal, anthelmintic [14][15][16][17][18], and insecticidal properties [19,20]. Some studies have also focused on L. camara essential oils, showing the high diversity in essential oil compositions depending on plant growth area.…”

Section: Introductionmentioning

confidence: 99%

Composition, Seasonal Variation, and Biological Activities of Lantana camara Essential Oils from Côte d’Ivoire

et al. 2020

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This work aims to study the variations in the composition of Lantana camara leaf, flower, and stem essential oils over two years. L. camara organs were harvested in Bregbo (East Côte d’Ivoire) each month from June 2015 to June 2017. The essential oils were obtained by hydrodistillation and characterized by GC-MS and 13C NMR. Eighty-four compounds accounting for 84.4–99.1% of the essential oils have been identified. The essential oils hydrodistillated from L. camara are dominated by sesquiterpenes such as (E)-β-caryophyllene and α-humulene, which were found in all samples. Some monoterpenes such as thymol, sabinene, and α-pinene were also present. Statistical analysis (principal component analysis and clustering) revealed a high variability in essential oil composition between the different organs and also within the studied periods, as the thymol proportion was higher during flowering and fruiting months. In addition, the stem, flower, and fruit essential oils were more concentrated in thymol than the leaf essential oils. The proportions of (E)-β-caryophyllene and α-humulene were strictly inverted with the thymol proportion throughout the harvest period or vegetative cycle. The antioxidant, anti-inflammatory and insecticidal activities of leaves and flowers essential oils were also studied. Results showed that L. camara leaf and flower essential oils displayed high antioxidant, anti-inflammatory and insecticidal activities.

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Chemical constituents and evaluation of cytotoxic and antifungal activity of Lantana camara essential oils

Cited by 24 publications

References 47 publications

Antimicrobial Activities of Lantana Camara Linn.

Antimicrobial Activities of Lantana Camara Linn.

Isolation, characterization and evaluation of antimicrobial and cytotoxic activity of estragole, obtained from the essential oil of croton zehntneri (euphorbiaceae)

Composition, Seasonal Variation, and Biological Activities of Lantana camara Essential Oils from Côte d’Ivoire

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