Chemical constituents and<i>in vitro</i>antioxidant activity of<i>Phyllanthus wightianus</i>

Priya, Olaganathan Siva; Viswanathan, M. B.; Balakrishna, Kediki; Venkatesan, M.

doi:10.1080/14786419.2010.517203

Cited by 18 publications

(4 citation statements)

References 37 publications

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“…Likewise, Priya et al 45 has studied the antioxidant activity of P. wightianus. By using standards, in vitro method and they found that P. wightianus methanol had a strong scavenging impact on 2, 2-diphenyl-2-picryl hydrazyl (DPPH) free radicals was 62.36%.…”

Section: Antioxidant Activity Of Beef Pattiesmentioning

confidence: 99%

Formulation and Evaluation of Phyllanthus Wightianus-Based Active Packaging Film for Meat Preservation

Xie,

Ahsan,

Tariq

et al. 2024

Preprint

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A biopolymer-based edible film was prepared using Phyllanthus wightianus to extend the shelf life of beef patties. For this purpose, the film was prepared by using polyvinyl alcohol (PVA, 5% W/V), carboxymethyl cellulose (CMC, 1% W/V), glycerol (0.1% V/V) as a plasticizer, flaxseed gel and P. wightianus extract @ 0, 1, 2 and 3% in various treatments. The film was analyzed at the interval of 0, 10, 20, and 30th days at 25°C for thickness, the film's opacity, degree of solubility and swelling, water vapor permeability, and Staphylococcus aureus and Escherichia coli antibacterial activity. After a month of storage study, the developed film was used to coat beef patties and analyzed for antioxidants, pH, peroxidation, and moisture. A total plate count test was performed for antimicrobial analysis, and beef patties were further evaluated for sensory evaluation parameters. The results showed that film has substantial antimicrobial potential suitable for longer storage and helpful in delaying the spoilage of beef patties by controlling lipid peroxidation and microbial growth of meat spoilage bacteria, especially S. aureus and E. coli. In conclusion, the films developed with 3% P. wightianus extract and flaxseed gel prolong the shelf life of beef patties throughout storage.

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Section: Antioxidant Activity Of Beef Pattiesmentioning

confidence: 99%

Formulation and Evaluation of Phyllanthus Wightianus-Based Active Packaging Film for Meat Preservation

Xie,

Ahsan,

Tariq

et al. 2024

Preprint

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“…Most of the anti-inflammatory, digestive, antinecrotic, neuroprotective and hepatoprotective drugs derived from natural origin have been reported to have antioxidant/radical scavenging mechanism as part of their activity. [6] The ingestion of natural antioxidants has been associated with the reduced risk of cancer, cardiovascular disease, diabetes and other diseases associated with ageing. [7] Hence, interest has been increased for finding antioxidants of plant source, which are safe and suitable for use in food and/or medicine.…”

Section: Introductionmentioning

confidence: 99%

Antioxidant properties of some selected Indian medicinal plants: Their correlation with total phenolic contents

Mohana¹,

Thippeswamy²,

Manjunath³

et al. 2013

Int J Green Pharm

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Background: Antioxidants play a major role in protecting the biological systems against oxidative stress, which is associated with development of many chronic diseases and disorders. Plants are the main sources of natural antioxidants in the form of phenolic compounds, which help human beings to deal with oxidative stress, caused by free radical damage. Aim: The present study aimed at the evaluation of antioxidant properties of extracts of different medicinal plants and their correlation with the total phenolic contents (TPCs). Materials and Methods: The selected plant materials were sequentially extracted with solvents with increasing polarity and analysed for their phytochemical constituents and antioxidant properties. The free radical scavenging activity of solvent extracts was assessed by 2,2-diphenyl-1-picrylhydrazyl assay and TPCs by Folin-Ciocalteu method. Results and Conclusions: In preliminary assay, 35 plants were screened for antioxidant properties, among them four plants were selected for the study. The methanol extracts of Acacia catechu (AC-ME), Adenanthera pavonia (AP-ME), Holopetelea integrifolia (HI-ME) and ethanol extract of Terminalia paniculata (TP-EE) showed highest antioxidant activity with 50% inhibitory concentration (IC 50 ) value ranging from 7.5 to 350 μg/ mL. The percentage radical scavenging activities of samples were compared to the standard butylated hydroxytoluene (BHT). The antioxidant activity of extracts and BHT in increasing order was HI-ME < AP-ME < TP-EE < BHT < AC-ME. A positive correlation was observed between antioxidant activity and TPCs. The results suggested that the phenolic compounds in extracts are most likely to be responsible for the observed antioxidant activity.

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“…It exhibits various biological properties, such as antimicrobial [17–19], larvicidal [20, 21], analgesic [22], wound healing [23], and antioxidant properties [24]. On the basis of the above information, the present investigation was focused on antimicrobial properties of different solvent leaf extracts and GC-MS analysis of bioactive extract of P. wightianus Müll.…”

Section: Introductionmentioning

confidence: 99%

Phyllanthus wightianusMüll. Arg.: A Potential Source for Natural Antimicrobial Agents

Srinivasan

Shivakumar

2014

BioMed Research International

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Phyllanthus wightianus belongs to Euphorbiaceae family having ethnobotanical importance. The present study deals with validating the antimicrobial potential of solvent leaf extracts of P. wightianus. 11 human bacterial pathogens (Bacillus subtilis, Streptococcus pneumoniae, Staphylococcus epidermidis, Proteus vulgaris, Pseudomonas aeruginosa, Klebsiella pneumoniae, Salmonella typhimurium, Escherichia coli, Shigella flexneri, Proteus vulgaris, and Serratia marcescens) and 4 fungal pathogens (Candida albicans, Cryptococcus neoformans, Mucor racemosus, and Aspergillus niger) were also challenged with solvent leaf extracts usingagar well and disc diffusion methods. Further, identification of the active component present in the bioactive extract was done using GC-MS analysis. Results show that all extracts exhibited broad spectrum (6–29 mm) of antibacterial activity on most of the tested organisms. The results highlight the fact that the well in agar method was more effective than disc diffusion method. Significant antimicrobial activity was detected in methanol extract against S. pneumoniae (29 mm) with MIC and MBC values of 15.62 μg/mL. GC-MS analysis revealed that 29 bioactive constituents were present in methanolic extract of P. wightianus, of which 9,12-octadecaenioic acid (peak area 22.82%; RT-23.97) and N-hexadecanoic acid (peak area 21.55% RT-21.796) are the major compounds. The findings of this study show that P. wightianus extracts may be used as an anti-infective agent in folklore medicine.

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Chemical constituents andin vitroantioxidant activity ofPhyllanthus wightianus

Cited by 18 publications

References 37 publications

Formulation and Evaluation of Phyllanthus Wightianus-Based Active Packaging Film for Meat Preservation

Formulation and Evaluation of Phyllanthus Wightianus-Based Active Packaging Film for Meat Preservation

Antioxidant properties of some selected Indian medicinal plants: Their correlation with total phenolic contents

Phyllanthus wightianusMüll. Arg.: A Potential Source for Natural Antimicrobial Agents

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