Chemical constituents, antioxidant and antimocrobial activity of essential oil ofPogostemon paniculatus(Willd.)

Abstract

The essential oil extracted from the leaves of Pogostemon paniculatus (Willd.) Benth. (Lamiaceae), was analysed by gas chromatography-mass spectrometry (GC-MS). Nineteen compounds constituting 85.36% of the total oil were identified in the oil. Patchouli alcohol (30.65%), α-guaiene (10.67%), β-guaiene (9.09%), caryophyllene (8.64%), eicosene (5.27%) were the major constituents present. The essential oil was analysed for antimicrobial activity by disc diffusion assay and minimum inhibition concentration against six bacteria and three fungi. Results showed inhibitory activity against some of the tested microorganisms. The essential oil was also tested for the DPPH free-radical scavenging activity and had an inhibitory concentration (IC(50)) value of 18.5 µg mL(-1).

Protective effect of aqueous seed extract of Vitis Vinifera against oxidative stress, inflammation and apoptosis in the pancreas of adult male rats with diabetes mellitus

“…However, biological effects of guanidine N,N-dimethyl has never been reported. Meanwhile, oxime methoxy-phenyl and seychellene have been suggested to play a role as anti-oxidant [35,36]. Benzene 3-methylcyclopentyl was proposed to display anti-inflammatory properties [37] and 9-octadecenamide, phenol was reported to display anti-oxidant properties [37].…”

Chemical constituents, antioxidant and cytotoxicity properties of Leonotis leonurus used in the folklore management of neurological disorders in the Eastern Cape, South Africa

“…Furthermore, the anticancer and antioxidant activity of 1-octadecene has been reported (Renukadevi et al 2011). Eicosene and 2-tetradecene, are compounds that are suspected to contribute to the anticancer, antimicrobial and antioxidant ability of plant extracts (Manoj et al 2012;Tiloke et al 2018).…”

Potential benefits of patchouli alcohol in prevention of human diseases: A mechanistic review

“…Patchouli oil has unique characteristics, including a long–lasting, woody, camphoraceous and earthy redolence [2] . It is listed as generally regarded as safe (GRAS) and so approved as a natural food additive by the US Food and Drug Administration [3] . Oil extracted from the whole aerial parts of patchouli consists of patchouli alcohol (PA) (55.7%), α-guaiene (13.1%), α-bulnesene (11.1%) and other compounds.…”