Chemical constituents from Eupatorium fortunei and their anti-inflammatory evaluation by in silico and experimental approaches

Anti‐inflammatory Polyketides from an Endophytic Fungus Chaetomium sp. UJN‐EF006 of Vaccinium bracteatum

“…As part of our recent years’ efforts to search for bioactive ingredients from medicinal herbs with dietary values, [8–11] we have lately isolated iridoids and lignans with diverse bioactivities as the major chemical constituents in the leaves of Vaccinium bracteatum [12] . Since plant‐derived endophytic fungi have emerged as an important source of bioactive natural products in the last two decades, [13–14] the chemical diversity of V. bracteatum metabolites has thus inspired us to start a project aiming to explore the bioactive metabolites produced by the endophytic fungi of this plant.…”

“…[5] In addition, the Chaetomium fungi are also famous in the scientific community for their ability to metabolize a variety of bioactive natural products especially cytochalasans and azaphilones, [6] and these two important groups of compounds have been considered to be suitable chemotaxonomic markers for genus Chaetomium. [7] As part of our recent years' efforts to search for bioactive ingredients from medicinal herbs with dietary values, [8][9][10][11] we have lately isolated iridoids and lignans with diverse bioactivities as the major chemical constituents in the leaves of Vaccinium bracteatum. [12] Since plant-derived endophytic fungi have emerged as an important source of bioactive natural products in the last two decades, [13][14] the chemical diversity of V. bracteatum metabolites has thus inspired us to start a project aiming to explore the bioactive metabolites produced by the endophytic fungi of this plant.…”