Chemical Constituents From the Ethyl Acetate Extract of Salvia hydrangea

Abstract

One new triterpenoid, 3β-O-(2-hydroxybenzoyl)-ursolic acid (1), and 11 known compounds, including 5 triterpenoids, 2 steroidal compounds, and 4 phenolic compounds were isolated from the ethyl acetate extract of the aerial parts of Salvia hydrangea. Their structures were elucidated based on the extensive spectroscopic data, including 1-dimensional and 2-dimensional nuclear magnetic resonance spectra, high resolution-electrospray ionization mass spectrometry, and by comparison with literature data. The antiprotozoal activity of compound 1 was evaluated against Trypanosoma brucei rhodesiense, Trypanosoma cruzi, Leishmania donovani, Plasmodium falciparum and showed no activities against all parasite tested.

Antibacterial potential of biosynthesized silver nanoparticles using Nepeta sessilifolia Bunge and Salvia hydrangea DC. ex Benth. extracts from the natural habitats of Iran's Rangelands

“…Among these, about 61 native species grow wild in Iran [ 26 ], of which 17 species are exclusive to Iran [ 31 ]. Since ancient times, salvia species have been used to treat more than 60 different diseases, from pain to epilepsy, and mainly to treat colds, bronchitis, tuberculosis, bleeding, and menstrual disorders [ 32 , 33 ]. In Iranian folk medicine, a wide range of biological activities of crude extracts, essential oils, and purified compounds of salvia species have been reported [ 34 ].…”

Phytochemical constituents and biological activities of Salvia macrosiphon Boiss.

“…Herein, focusing on discovering bioactive secondary metabolites from Iranian Salvia species [ 17 ], we studied the aerial parts of Salvia macrosiphon Boiss., Wild sage known as “Marvak” in Persian [ 18 ]. The plant is an endemic species growing in the west and center of Iran, and has been used in Iranian traditional medicine as diuretic, carminative and anti-flatulent [ 19 ].…”