Chemical constituents from the fungus Phellinus baumii and their anti-inflammatory activity

Zhao, Yongtao; Dong, Xin-Yue; Ning, Jin-Lei; Jin, Ying-Xue; Wang, Guo-Kai; Feng, Tao

doi:10.1016/j.phytol.2022.12.017

Cited by 8 publications

(3 citation statements)

References 28 publications

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“…Phellinbaumins A and D from the fungus Phellinus baumii were found to display moderate inhibitory activity on NO production in a murine model, with IC 50 values of 31.7 and 24.3 μM, respectively [ 111 ]. Two new ergosterol derivatives (chlamydosterols A and B) and three known to have anti-inflammatory activity were isolated from another endophytic fungus— Fusarium chlamydosporum .…”

Section: Fungi With Anti-inflammatory Potentialmentioning

confidence: 99%

The Plethora of Microbes with Anti-Inflammatory Activities

Tsvetanova

2024

IJMS

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Inflammation, which has important functions in human defense systems and in maintaining the dynamic homeostasis of the body, has become a major risk factor for the progression of many chronic diseases. Although the applied medical products alleviate the general status, they still exert adverse effects in the long term. For this reason, the solution should be sought in more harmless and affordable agents. Microorganisms offer a wide range of active substances with anti-inflammatory properties. They confer important advantages such as their renewable and inexhaustible nature. This review aims to provide the most recent updates on microorganisms of different types and genera, being carriers of anti-inflammatory activity.

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Section: Fungi With Anti-inflammatory Potentialmentioning

confidence: 99%

The Plethora of Microbes with Anti-Inflammatory Activities

Tsvetanova

2024

IJMS

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“…Phellinbaumins A and D from the fungus Phellinus baumii were found to display moderate inhibitory activity on NO production in a murine model, with IC 50 values of 31.7 and 24.3 µM, respectively [111]. Two new ergosterol derivatives (chlamydosterols A and B) and three known to have anti-inflammatory activity were isolated from another endophytic fungus-Fusarium chlamydosporum.…”

Section: Fungi With Anti-inflammatory Potentialmentioning

confidence: 99%

The Plethora of Microbes with Anti-inflammatory Activities

Tsvetanova

2024

Preprint

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Inflammation which has important functions in human defense systems and in maintaining the dynamic homeostasis of the body has become a major risk factor for the progression of many chronic diseases. Although the applied medical products alleviate the general status, they still exert adverse effects in the long term. For this reason, the solution should be sought in more harmless and affordable agents. Microorganisms offer a wide range of active substances with anti-inflammatory properties. They propose important advantages such as renewable and inexhaustible nature. This review aims at the most recent updates on the microorganisms of different type and genera being carriers of anti-inflammatory activity.

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“…Meanwhile, the main active component of PL is a polysaccharide that has a variety of biological activities. These include anti-oxidation [ 8 ], antitumor [ 9 ], immunomodulatory [ 10 , 11 ], anti-inflammatory [ 12 ], anti-virus [ 13 ], free radical scavenging ability [ 14 ], and antibacterial effects [ 15 ]. An increasing number of structurally diverse polysaccharides have been obtained from Phellinus linteus cotyledons, Phellinus linteus mycelium, and fermentation broth by a large number of extraction and separation methods, such as hot water extraction, ultrasonic extraction, enzymatic extraction, and a large number of purification methods such as ethanol precipitation and packed column chromatography [ 16 ].…”

Section: Introductionmentioning

confidence: 99%

Study on Extraction, Physicochemical Properties, and Bacterio-Static Activity of Polysaccharides from Phellinus linteus

Gao

Zhang

et al. 2023

Molecules

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We optimized an ultrasound-assisted extraction process of Phellinus linteus mycelium polysaccharides (PLPs) and studied their monosaccharide composition and bacteriostatic properties. Based on a single-factor experiment, a three-factor, three-level Box–Behnken design was used to optimize the ultrasound-assisted extraction process of PLP, using the yield of PLP as the index. The chemical composition and monosaccharide composition of PLP were determined by chemical analysis and HPLC analysis, respectively. Microscopic morphological analysis of the surface of PLP was performed via swept-surface electron microscopy. The bacteriostatic properties of PLP were determined using the spectrophotometric turbidimetric method. The results showed that the best extraction process of PLP with ultrasonic assistance achieved a result of 1:42 g/mL. In this method, the ultrasonic temperature was 60 °C, ultrasonic extraction was performed for 20 min, and the yield of PLP was 12.98%. The monosaccharide composition of PLP mainly contains glucose (Glc), mannose (Man), galactose (Gal), and glucuronic acid (GlcA). The intracellular polysaccharide of Phellinus igniarius Mycelia (PIP) is an irregular spherical accumulation, the surface is rough and not smooth, and the extracellular polysaccharide (PEP) is a crumbly accumulation. PIP has a stronger inhibitory ability for S. aureus and E. coli and a slightly weaker inhibitory effect for B. subtilis; the inhibitory effect of PEP on S. aureus, E. coli, and B. subtilis is slightly inferior to that of PIP.

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Chemical constituents from the fungus Phellinus baumii and their anti-inflammatory activity

Cited by 8 publications

References 28 publications

The Plethora of Microbes with Anti-Inflammatory Activities

The Plethora of Microbes with Anti-Inflammatory Activities

The Plethora of Microbes with Anti-inflammatory Activities

Study on Extraction, Physicochemical Properties, and Bacterio-Static Activity of Polysaccharides from Phellinus linteus

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