Chemical Constituents of Cannabis sativa L. Root

Vinyl Acetate Casts of Emphysematous Rat Lungs

“…In corrosion models of emphysematous human lungs, a notable abnormality was a loss of alveoli on the respiratory bronchioles which appeared as smooth and bulging structures (7), similar to what was observed in the present study. Emphysema has been reported to be due to loss of alveoli, resulting in enlargement of respiratory bronchioles, alveolar ducts, and lung distension ( 5 ) .…”

“…Latex casts were used to study acinar changes in human emphysema (7). Latex casts were used to study acinar changes in human emphysema (7).…”

Secondary metabolism in cannabis

“…Pharmacological effects have been detected for some cannabis terpenes and they may synergize the effects of the cannabinoids (Burstein et al 1975;McPartland and Mediavilla 2002). Terpenes have been detected and isolated from the essential oil from flowers roots (Slatkin et al 1971) and leaves (Bercht et al 1976;Hendriks et al 1978); however, the glandular hairs are the main site of localization (Malingre et al 1975). …”

“…The phenolic amides have cytotoxic (Chen et al 2006), anti-inflammatory (Kim et al 2003), antineoplastic (Ma et al 2004), cardiovascular (Yusuf et al 1992) and mild analgesic activity (Slatkin et al 1971). For the lignanamides grossamide, cannabisin-D and -G a cytotoxic activity was reported .…”

Cultivation and Breeding of Cannabis sativa L. for Preparation of Standardized Extracts for Medicinal Purposes

“…Over 200 different terpenoids have been reported in C. sativa and most of them have been isolated from the essential oil from flowers (Ross and ElSohly 1996), from roots (Slatkin et al 1971), leaves , and glandular trichomes (Kim and Mahlberg 2003). The volatile mono-and sesquiterpenoids are responsible for the various flavours found in Cannabis (Russo 2011).…”