Chemical constituents of Entandrophragma angolense and their anti-inflammatory activity

Youn, Isoo; Han, Kyu-Yeon; Gurgul, Aleksandra; Wu, Zhen‐Long; Lee, Hyun; Che, Chun‐Tao

doi:10.1016/j.phytochem.2022.113276

Cited by 4 publications

(3 citation statements)

References 50 publications

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“…Preussia sp., like other genera found, is used in biotechnology both due to its antiinflammatory effects and in enhancing the growth of agricultural products [61,62]. Therefore, like Pestalotiopsis sp., it results in a new possibility of obtaining biotechnological products.…”

Section: Discussionmentioning

confidence: 99%

Characterization of the Cultivable Microbiota Components of Marine Bioaerosols in the North Tropical Atlantic

Moura,

Ayres,

Brito

et al. 2023

Atmosphere

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Microorganisms are key to balancing marine ecosystems and have complex interactions at the ocean–atmosphere interface, affecting global climate and human health. This research investigated the diversity of cultivable bacteria and fungi in marine bioaerosols in the North Tropical Atlantic Ocean. Using the technique of spontaneous sedimentation in selective culture media, samples were collected during oceanographic expeditions. After isolation and purification, microbial strains were identified by phenotypic and genetic analyses. Fungi isolated included Acrophialophora, Aspergillus, Chrysosporium, Cladosporium, Fonsecaea, Mucor, Rhodotorula, Schizophyllum, Stemphylium, Candida, Curvularia, Cystobasidium, Exophiala, Neotestudina, Penicillium, Pestalotiopsis, and Preussia. The bacterial isolates belonged to the Bacillota, Pseudomonadota, Enterobacteriaceae family, Bacillus genus, and Serratia liquefaciens groups. About 40% of bacteria and 42% of fungi were identified as potential human pathogens, suggesting a relationship between human actions and the microbiota present in bioaerosols on the high seas. Sea surface temperature (SST) and wind speed influenced microorganisms. More studies and analyses in different scenarios should be conducted considering environmental and climate variables in order to deepen knowledge and generate information on the subject, so that standards can be established, and quality parameters determined.

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Section: Discussionmentioning

confidence: 99%

Characterization of the Cultivable Microbiota Components of Marine Bioaerosols in the North Tropical Atlantic

Moura,

Ayres,

Brito

et al. 2023

Atmosphere

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“…All the experiments were performed in triplicates and analysed using SigmaPlot 14.0 (Systat Software, CA, USA) unless otherwise stated. 16 Percentage inhibition of Nitric oxide was calculated relative to DMSO.…”

Section: Nitric Oxide Inhibitory Assaymentioning

confidence: 99%

“…Coloured formazan was measured at 490 nm using a microplate reader. 16 Percentage cell viability was evaluated relative to DMSO.…”

Section: Toxicity Assay On Murine Macrophage Cellsmentioning

confidence: 99%

Antiproliferative Potential of Ethanol Leaf Extract of Motandra guineensis (Thonn.) A.DC. (Apocynaceae) against Human Melanoma and Ovarian Cancer Cells

2024

TJNPR

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In ethnomedicine, Motandra guineensis (Thonn.) A.DC. (Apocynaceae) is used to massage abscessed gums and manage pain. This study aimed to evaluate the antiproliferative effect of leaves of M. guineensis against human ovarian (OVCAR3) and melanoma (MDA-MB-435) skin cancer cells. Crude ethanol extract and fractions of M. guineensis leaves were evaluated for antiproliferative effect on OVCAR3 and MDA-MB-435 cells using cell viability assay at 2 and 20 µg/ml. In addition, the inhibitory effect of extract and fractions on nitric oxide (NO) production with lipopolysaccharide (LPS) stimulation (Greiss assay) on murine macrophage cells (RAW 264.7) at 0.3125 -10 µg/ml was evaluated. Cell viability was evaluated using murine macrophage cells while toxicity assessment was done on Vero cells. Antiproliferative activity profile (% cell death) of extract and fractions followed the order: butanol (30% and 23%) > aqueous (28% and 21%) > ethyl acetate (22% and 19%) > crude (22% and 0%) at 20 μg/ml in OVCAR3 and MDA-MB-435 cell lines respectively. Percentage NO inhibitory activity showed hexane fraction with the highest activity and aqueous fraction with the least activity at 10 μg/ml. Extract and fractions were less toxic in Vero cells when compared to the standard drug, Tamoxifen. Toxicity assessment using murine macrophage cells showed no significant difference in cell viability when compared to standard. Results indicate antiproliferative potential, NO inhibitory potential and safety of crude ethanol leaf extract and fractions of M. guineensis.

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Review of natural plant-derived seco-triterpenoids and derived saponins from 2020 to 2023: new compounds, distributions, diverse activities and structure–activity relationships

Wei,

Wang,

Liu

et al. 2024

Phytochem Rev

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Chemical constituents of Entandrophragma angolense and their anti-inflammatory activity

Cited by 4 publications

References 50 publications

Characterization of the Cultivable Microbiota Components of Marine Bioaerosols in the North Tropical Atlantic

Characterization of the Cultivable Microbiota Components of Marine Bioaerosols in the North Tropical Atlantic

Antiproliferative Potential of Ethanol Leaf Extract of Motandra guineensis (Thonn.) A.DC. (Apocynaceae) against Human Melanoma and Ovarian Cancer Cells

Review of natural plant-derived seco-triterpenoids and derived saponins from 2020 to 2023: new compounds, distributions, diverse activities and structure–activity relationships

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