Chemical Constituents of Liposoluble Extract of Spiraea Hypericifolia L.

Abstract

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Non-Targeted Screening of Metabolites in Aqueous-Ethanol Extract from Spiraea hypericifolia (Rosaceae) Using LC-HRMS

“…The major biologically active compounds of the leaves of S. hypericifolia were flavonols and catechins, whose levels reached 32.6 and 1.8 mg/g, respectively [8]. By contrast, according to research by A.A. Kudaibergen et al [3], the concentration of flavonoids in the underground part of S. hy- Our results on the concentrations of biologically active compounds in the extract from the aerial part of S. hypericifolia are partially consistent with the literature data. For instance, in separate analyses of the bark, stems, leaves, and root cores of S. hypericifolia, N.D. Storozhenko [8] found that the main biologically active compounds in the organs of the aboveground and underground parts of the plant are flavonoids: flavonols, flavans, and flavones.…”

“…The major biologically active compounds of the leaves of S. hypericifolia were flavonols and catechins, whose lev-els reached 32.6 and 1.8 mg/g, respectively [8]. By contrast, according to research by A.A. Kudaibergen et al [3], the concentration of flavonoids in the underground part of S. hypericifolia is 53.6 mg/(g of total extract), while their concentration in the aboveground part does not exceed 7.7 mg/g. The discrepancy in the results is possibly due to the fact that the accumulation of these substances is influenced by environmental factors associated with the ontogenetic state of the plant at the time of sampling of the plant material; another possible reason is the choice of methods for analyzing the extracts.…”

“…It can be found in the Sayan Mountains up to 1400 m above sea level and in the Altai and Tuva up to 1650 m above sea level [ 1 , 2 ]. The bulk of S. hypericifolia ’s geographical range is situated in Eurasia, and this plant is considered one of the most evolutionarily developed members of this genus [ 3 ]. Species of the genus Spiraea , including S. hypericifolia , are ornamental plants and are often used to decorate gardens and parks [ 1 ].…”