Chemical constituents of Rubia tibetica Hook. f. from Tibetan medicine and cytotoxic activity evaluation

Gu, Min-Min; Li, Qing; Zhang, Yu; Wu, Hong-Wei; Shao, Yuan-Ling; Han, Hong-Ping; Liao, Zhi-Xin

doi:10.1016/j.fitote.2024.105961

Fitoterapia

2024

DOI: 10.1016/j.fitote.2024.105961

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Chemical constituents of Rubia tibetica Hook. f. from Tibetan medicine and cytotoxic activity evaluation

Min-Min Gu,

Qing Li,

Yu Zhang

et al.

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2024

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Identification of New Compounds from the Roots of Rubia tibetica Hook. f.

Li,

Gu,

Zhang

et al. 2024

Chemistry & Biodiversity

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Rubia tibetica Hook. f is a traditional Tibetan medicinal plant, with its roots serving as the primary medicinal part. Two new compounds, Rubiaxylm C and E (1 and 3), and one new natural compound, Rubiaxylm D (2) were isolated from R. tibetica, along with five known compounds (4–8). The structures of the previously undescribed compounds were elucidated by HR‐ESIMS, 1D/2D NMR spectroscopic data and electronic circular dichroism calculations. Compound 1 is a rare anthrone substituted with a carbonyl group at position 1. Furthermore, all isolated compounds were tested for their cytotoxicity against HepG2 cell lines.

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Identification of New Compounds from the Roots of Rubia tibetica Hook. f.

Li,

Gu,

Zhang

et al. 2024

Chemistry & Biodiversity

View full text Add to dashboard Cite

show abstract

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Chemical constituents of Rubia tibetica Hook. f. from Tibetan medicine and cytotoxic activity evaluation

Cited by 1 publication

References 25 publications

Identification of New Compounds from the Roots of Rubia tibetica Hook. f.

Identification of New Compounds from the Roots of Rubia tibetica Hook. f.

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