Chemical constituents of the rhizomes of Hedychium coronarium and their inhibitory effect on the pro-inflammatory cytokines production LPS-stimulated in bone marrow-derived dendritic cells

Kiệm, Phan Văn; Thuy, Nguyen Thu; Anh, Hoang Le Tuan; Nhiệm, Nguyễn Xuân; Minh, Châu Văn; Yến, Phạm Hải; Ban, Ninh Khac; Hang, Dan Thuy; Tài, Bùi Hữu; Tuyen, Nguyen Van; Mathema, Vivek Bhakta; Koh, Young‐Sang; Kim, Young Ho

doi:10.1016/j.bmcl.2011.09.129

Cited by 50 publications

(24 citation statements)

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“…Stigmasterol was reported previously from other two Hedychium species of H. forrestii (Liu et al 2004) and H. coronarium (Kiem et al 2011) and also found in many other plant families including Zingiberaceae such as Renealmia (Lognay et al 1989), Alpinia Phan & Phan 2004;Phan et al 2012Phan et al , 2007Phan et al , 2005, Zingiber (Peng et al 2007), Etlingera (Mahdavi 2014;Yahya et al 2011) and Curcuma (Shamim et al 2011). To the best of our knowledge, this is the first time sitostenone and stigmast-4-ene-3,6-dione have been isolated from genus Hedychium, which contributes to the database of steroids from Hedychium.…”

Section: Resultsmentioning

confidence: 99%

“…They are distributed in five plants namely H. spicatum (Sravani et al 2014(Sravani et al , 2012, H. coronarium (Kiem et al 2011), H. chrysoleucum (Luo et al 2009), H. forrestii (Liu et al 2004) and H. villosum (Xiao et al 2001). Xanthones and flavonoids which have similar structures can be found in Hedychium gardnerianum (Carvalho et al 2003;De Medeiros et al 2008).…”

Section: Introductionmentioning

confidence: 99%

“…To date, eight Hedychium have been subjected to phytochemical investigations namely H. coronarium (Chen et al 2013), H. gardnerianum (Kumrit et al 2010), H. spicatum (Reddy et al 2009), H. chrysoleucum (Luo et al 2009), H. forrestii (Liu et al 2004), H. villosum (Xiao et al 2001), H. yunnanense (Li et al 2016) and H. longipetalum (Zhao et al 2015) and all of them were found to contain labdane diterpenes. Many sesquiterpenoids identified from the essential oils such as cryptomeridiol, β-eudesmol, oplopanone, elemol, oplodiol, caryophyllene oxide, transnerolidol and α-eudesmol were also chromatographically isolated from the H. spicatum (Suresh et al 2013), H. coronarium (Kiem et al 2011), H. chrysoleucum (Luo et al 2009), H. gardnerianum (Carvalho et al 2003) and H. yunnanense (Zhao et al 1995). Lupeol as a tritepenoid was isolated once from Hedychium i.e.…”

Section: Introductionmentioning

confidence: 99%

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Phytochemical Study of Hedychium malayanum (Zingiberaceae)

Abdo

Ahmad²,

Din

et al. 2017

JSM

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Phytochemical Study of Hedychium malayanum (Zingiberaceae)

Abdo

Ahmad²,

Din

et al. 2017

JSM

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“…The inhibitory effect on the pro-inflammatory cytokines production is the parameter to examine the inflammatory activity. The test ofh the isolates from H. coronarium as the anti-inflammatory agent were evaluated by Kiem et al, 2011 26 . The result showed that the hedyforrestin C potently inhibited IL-6 and IL-12 production LPSstimulated BMDCs.…”

Section: Anti-inflammatory Activitymentioning

confidence: 99%

Botanical, Phytochemical and Pharmacological Properties of Hedychium (Zingiberaceae) – A Review

2014

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Zingiberaceae is one of the most widely distributed plants in tropic and subtropic area, about 19 genus and 375 species weredistributed in Indonesia. Based on empirical data, some of the plants were used traditionally to treat various diseases. Nowadays, Zingiberaceae plants are extensively studied for their phytochemistry and pharmacological properties included genus Hedychium. The various bioactive compounds were isolated from these plants and they were known to have the pharmacological effect. This review showed that Hedychium plants were prospective as a natural product medicine.

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“…An essential oil from the roots is carminative and has anthelmintic indications [6]. Extracts of H. coronarium have been used for the treatment of inflammation, skin diseases, headache, and sharp pain due to rheumatism in traditional medicine [7]. The plant also possessed analgesic and neuropharmacological [8,9], anti-inflammatory [9], antimicrobial [10,11] and cytotoxic [11] activities.…”

Section: Introductionmentioning

confidence: 99%

Composition of essential oils of four Hedychiumspecies from Vietnam

Thanh

Đài

Thăng

et al. 2014

Chemistry Central Journal

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BackgroundVietnam is a country blessed with many medicinal plants widely used as food and for medicinal purposes, and they contain a host of active substances that contribute to health. However, the analysis of chemical constituents of these plant species has not been subject of literature discussion.ResultsIn this study, the chemical compositions of essential oils of four Hedychium species, obtained by hydrodistillation, were determined by means of gas chromatography-flame ionization detector (GC-FID) and gas chromatography–mass spectrometry (GC-MS) techniques. Individually, α-pinene (52.5%) and β-pinene (31.8%) were present in the leaf oil of Hedychium stenopetalum Lodd., while linalool (45.2%), (E)-nerolidol (8.7%) and α-pinene (5.0%) were identified in the root. The leaf of Hedychium coronarium J. König was characterized by β-pinene (20.0%), linalool (15.8%), 1,8-cineole (10.7%), α-pinene (10.1%) and α-terpineol (8.6%); while β-pinene (23.6%), α-humulene (17.1%) and β-caryophyllene (13.0%) were identified in the root. Hedychium flavum Roxb., gave oil whose major compounds were β-pinene (22.5%), α-humulene (15.7%) and β-caryophyllene (10.4%) in the leaf; α-humulene (18.9%), β-caryophyllene (11.8%) and β-pinene (11.2%) in the stem, as well as β-pinene (21.8%), linalool (17.5%) and 1,8-cineole (13.5%) in the root. The main constituents of Hedychium ellipticum Buch.-Ham. ex Smith were (E)-nerolidol (15.9%), β-pinene (11.8%) and bornyl acetate (9.2%) in the leaf with 1,8-cineole (40.8%), α-pinene (18.3%) and β-pinene (11.0%) occurring in the root.ConclusionsUbiquitous monoterpenes and sesquiterpenes were identified as characteristic markers for Hedychium species. This work is of great importance for the evaluation of Hedychium essential oils grown in Vietnam.Electronic supplementary materialThe online version of this article (doi:10.1186/s13065-014-0054-3) contains supplementary material, which is available to authorized users.

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Chemical constituents of the rhizomes of Hedychium coronarium and their inhibitory effect on the pro-inflammatory cytokines production LPS-stimulated in bone marrow-derived dendritic cells

Cited by 50 publications

References 21 publications

Phytochemical Study of Hedychium malayanum (Zingiberaceae)

Phytochemical Study of Hedychium malayanum (Zingiberaceae)

Botanical, Phytochemical and Pharmacological Properties of Hedychium (Zingiberaceae) – A Review

Composition of essential oils of four Hedychiumspecies from Vietnam

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