Chemical Constituents of the Roots of Anemone altaica Fisch. ex C. A. Mey.

Abstract

The roots of Anemone altaica Fisch. ex C. A. Mey. have been used in the treatment of epilepsia, neurasthenia, and arthritis in Chinese folk medicine for a long time. In order to find new and bioactive compounds, the chemical constituents of the roots of A. altaica were investigated and nine compounds were isolated from the EtOH extract of this plant. On the basis of spectroscopic methods, the structures of these compounds were elucidated as 4-(9H-β-carbolin-1-yl)-4-oxo-butyric acid (1), carboxymethyl isoferulate (2), isoferulic acid (3), cirsiumaldehyde (4), 5-hydroxy-4-oxo-pentanoic acid (5), triacontane (6), palmic acid (7), β-sitosterol (8), and daucosterol (9). Among them, 1 and 2 were new compounds, and 3 and 4 were obtained from this genus for the first time.

Isolation and Structure Elucidation of Olea Europaea

“…In thin layer chromatography (TLC) analysis, compound 4 showed Rf value 0.5 in solvent system n-Hexane: Methanol (80:20) in the form of single band on silica gel plate. Uridine has identical spectral data and chemical properties to those reported in earlier for uridine [23][24][25][26].…”

Anemone altaica Induces Apoptosis in Human Osteosarcoma Cells

“…A. altaica grows widespread throughout Northern Asia and Europe. Modern pharmacological studies have suggested the potential anti-inflammatory and analgesic properties of the A. altaica, which has long been used in the treatment of epilepsy, neurasthenia and arthritis in traditional Chinese medicine (Zou et al, 2005). Previous studies were only limited to the study of the chemical constituents and essential oils of A. altaica.…”

“…Previous studies were only limited to the study of the chemical constituents and essential oils of A. altaica. Isolation, purification and structural identification of some small-molecule active ingredients were the focus of previous studies (Feng, 1998;Zou and Yang, 2008;Man et al, 2012). However, in various areas of cancer research, A. altaica extract has not been reported to exhibit antitumor properties.…”

Study on <i>Limonium aureum</i> Endophytic Fungi and its Antibacterial Activity

“…Endophytic fungi is some fungi that lives in all kinds of tissue and organ internal or intercellular space in healthy plants with certain stage or the whole stage of its life history [5]. Endophytic fungi can produce some chemical substances, which its structure is similar with host plant, and many compounds have novel structural framework [6]. In 1993, an endophytic fungi isolated from Taxomyces andreanae produced the bioactive compounds, taxol and taxane, just like the host plant.…”