TJNPR 2018
DOI: 10.26538/tjnpr/v2i8.2
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Chemical constituents of the Stem Bark of Acacia ataxacantha (Fabaceae)

Abstract: ethylacetate soluble fraction of the stem bark of Acacia nilotica afforded a novel protein kinase inhibitory activity of two phenolic compounds isolated. 16 As part of our continuing studies of the genus Acacia, for protein kinase inhibitory constituents, we report herein the isolation of the triterpenoid: lupenol and α-spinasterol from the chloroform extract of the stem bark of Acacia ataxacantha, the two compounds were inactive against a panel of disease related protein kinases.

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“…This is particularly true in the field of cancer, immunosuppressive, and metabolism-related diseases, where naturederived products have played a crucial role in novel drug discovery and development. 2 The tribal populations of Chittagong Hill Tracts, Bangladesh, are dependent on the traditional tribal healers and on the use of various native medicinal plants for the treatment of a number of diseases for many years. 3…”
Section: Introductionmentioning
confidence: 99%
“…This is particularly true in the field of cancer, immunosuppressive, and metabolism-related diseases, where naturederived products have played a crucial role in novel drug discovery and development. 2 The tribal populations of Chittagong Hill Tracts, Bangladesh, are dependent on the traditional tribal healers and on the use of various native medicinal plants for the treatment of a number of diseases for many years. 3…”
Section: Introductionmentioning
confidence: 99%