Chemical constituents of the whole plants of Saussurea medusa

Abstract

The chemical constituents of the traditional Tibetan medicine of Saussurea medusa Maxim. (Compositae) were investigated and a new flavonoid glucoside, together with 14 known compounds, was isolated. The structure of the new compound was established as 6 00 -Ocrotonoylhomoplantaginin by using one-and two-dimensional nuclear magnetic resonance spectroscopy and mass spectrometry analyses.

Development of an UPLC-QTOF-MS method for qualitative and quantitative analysis ofSaussurea eopygmaea

“…By comparison the high resolution MS, MS/MS spectra data and retention time with those of authentic compounds, six other peaks could be tentatively identified to be syringinoside (9) [31], scopolin (10) [32], caffeic acid (11) [33], umbelliferone (12) [34], fraxetin-8-O-β-D-glucopyranoside (13) [35] and apigenin-7-O-rutinoside (14) [36] by matching the empirical molecular formula of the [M-H] − ion and the product ions in MS/MS with those in the literature. The structures of these compounds are depicted in Fig.…”

Tibetan medicine: a unique heritage of person-centered medicine

“…While research has been conducted covering the ecology and botanical strengths of Tibetan regions [15,[21][22][23][24][25][26][27][28][29], it is important to study more deeply into the pharmaceutical potentials of such materials. A large amount of research is centered around finding active constituents within specific Tibetan medical ingredients [30][31][32][33][34][35][36][37][38][39][40][41]. This has benefit as it may lead to the development of revolutionary drugs.…”

Imperatorin–pharmacological meaning and analytical clues: profound investigation

“… Apiaceae China For pyrexia, rheumatism, headache and convulsions (Kang et al 2008 ) Saussurea medusa Maxim. Compositae Asia, Europe, North America For anthrax, apoplexy, rheumatic arthritis and altitude sickness (Dawa et al 2009 ) Aegle marmelos Correa Rutaceae Southeast Asia In the treatment of malaria, diabetes, dyspepsia, constipation and body heating problems (Mishra et al 2010 ) Clausena anisata (Willd.) Hook.…”