Chemical Constituents of Vigna luteola and Their Anti-inflammatory Bioactivity

Lam, Sio Hong; Li, Yue Chiun; Kuo, Ping Chung; Hwang, Tsong‐Long; Yang, Mei; Wang, Chien Chiao; Tzen, Jason T. C.

doi:10.3390/molecules24071371

Cited by 13 publications

(2 citation statements)

References 41 publications

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“…Twenty-two known compounds were identified as quercetin-3- O - β -D-rhamnopyranoside ( 4 ) [ 17 ], 6-methoxy-naringenin ( 5 ) [ 18 ], 6-methoxy-kaempferol ( 6 ) [ 19 ], kaempferol ( 7 ) [ 20 ], apigenin ( 8 ) [ 21 ], abscisic acid ( 9 ) [ 22 ], (+)-dehydrovomifoliol ( 10 ) [ 23 ], grasshopper ketone ( 11 ) [ 24 ], roseoside ( 12 ) [ 25 ], citroside A ( 13 ) [ 23 ], 4′-(6-amino-9 H -purin-9-yl)pentan-2′-one ( 14 ) [ 26 ], seco-( S -Pro- R -Val) (1 5 ) [ 27 ], cyclo-( L -Pro- L -Ala) ( 16 ) [ 28 ], 3-methoxyl-1 H -pyrrole ( 17 ) [ 29 ], cyclo-(Ala-Val) ( 18 ) [ 30 ], indole-3-carboxyl- β -D-glucopyranoside ( 19 ) [ 31 ], uridine ( 20 ) [ 32 ], thymidine ( 21 ) [ 33 ], adenosine ( 22 ) [ 34 ], hypoxanthine ( 23 ) [ 35 ], aurantiamide acetate ( 24 ) [ 36 ], and L -pyroglutamic acid methyl ester ( 25 ) [ 37 ].…”

Section: Resultsmentioning

confidence: 99%

Chemical Constituents from the Flowers of Carthamus tinctorius L. and Their Lung Protective Activity

et al. 2022

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A new flavonoid, saffloflavanside (1), a new sesquiterpene, safflomegastigside (2), and a new amide, saffloamide (3), together with twenty-two known compounds (4–25), were isolated from the flowers of Carthamus tinctorius L. Their structures were determined based on interpretation of their spectroscopic data and comparison with those reported in the literature. The protective effects against lipopolysaccharide (LPS)-stimulated damage on human normal lung epithelial (BEAS-2B) cells of the compounds were evaluated using MTT assay and cellular immunofluorescence assay. The results showed that compounds 2–3, 8–11, and 15–19 exhibited protective effects against LPS-induced damage to BEAS-2B cells. Moreover, compounds 2–3, 8–11, and 15–19 can significantly downregulate the level of nuclear translocation of NF-κB p-p65. In summary, this study revealed chemical constituents with lung protective activity from C. tinctorius, which may be developed as a drug for the treatment of lung injury.

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Section: Resultsmentioning

confidence: 99%

Chemical Constituents from the Flowers of Carthamus tinctorius L. and Their Lung Protective Activity

et al. 2022

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“…However, almost all the efforts and resources invested in agriculture during the last century were focused on improving the yield, resistance and quality of a few specific staple crops. Neglected landraces are regarded as having interesting potential, and recent studies have demonstrated that some wild legumes can be an important target to develop modern functional foods because they possess various bioactive molecules that interact positively with human health [2][3][4][5]. Among these, members of the Vigna genus show a growing social and economic importance in several African regions, especially where the local population is not able to afford animal proteins [6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Revisiting the Domestication Process of African Vigna Species (Fabaceae): Background, Perspectives and Challenges

Panzeri

Nissim

Labra

et al. 2022

Plants

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Legumes are one of the most economically important and biodiverse families in plants recognised as the basis to develop functional foods. Among these, the Vigna genus stands out as a good representative because of its relatively recent African origin as well as its outstanding potential. Africa is a great biodiversity centre in which a great number of species are spread, but only three of them, Vigna unguiculata, Vigna subterranea and Vigna vexillata, were successfully domesticated. This review aims at analysing and valorising these species by considering the perspective of human activity and what effects it exerts. For each species, we revised the origin history and gave a focus on where, when and how many times domestication occurred. We provided a brief summary of bioactive compounds naturally occurring in these species that are fundamental for human wellbeing. The great number of wild lineages is a key point to improve landraces since the domestication process caused a loss of gene diversity. Their genomes hide a precious gene pool yet mostly unexplored, and genes lost during human activity can be recovered from the wild lineages and reintroduced in cultivated forms through modern technologies. Finally, we describe how all this information is game-changing to the design of future crops by domesticating de novo.

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