Chemical cystitis due to crystal violet dye: a case report

Hashimoto, Takeshi; Ohori, Makoto; Kashima, Takeshi; Yamamoto, Hirotaka; Tachibana, Masaaki

doi:10.1186/1752-1947-7-145

Cited by 6 publications

(3 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…CV dye was commonly used for the treatment of oral and vaginal candidiasis or for sterilization during operations up to the 1960s. CV is potentially toxic to mucosal membranes (Hashimoto et al ., ). A study showed that CV instilled into the bladder of a 47‐year‐old Japanese woman to confirm the presence of vesicovaginal fistula, produced gross hematuria, frequent urination and lower abdominal pain (Hashimoto et al ., ).…”

Section: Triphenylmethane Dyesmentioning

confidence: 99%

“…CV is potentially toxic to mucosal membranes (Hashimoto et al, 2013). A study showed that CV instilled into the bladder of a 47-year-old Japanese woman to confirm the presence of vesicovaginal fistula, produced gross hematuria, frequent urination and lower abdominal pain (Hashimoto et al, 2013). Cystoscopy revealed desquamated epithelial cells and a hemorrhagic bladder wall.…”

Section: Crystal Violet and Gentian Violetmentioning

confidence: 99%

See 1 more Smart Citation

Toxicity of imine–iminium dyes and pigments: electron transfer, radicals, oxidative stress and other physiological effects

Kovacic

Somanathan

2014

J of Applied Toxicology

View full text Add to dashboard Cite

Although conjugation is well known as an important contributor to color, there is scant recognition concerning involvement of imine and iminium functions in the physiological effects of this class of dyes and pigments. The group includes the dyes methylene blue, rhodamine, malachite green, fuchsin, crystal violet, auramine and cyanins, in addition to the pigments consisting of pyocyanine, phthalocyanine and pheophytin. The physiological effects consist of both toxicity and beneficial aspects. The unifying theme of electron transfer-reactive oxygen species-oxidative stress is used as the rationale in both cases. Toxicity is frequently prevented or alleviated by antioxidants. The apparent dichotomy of methylene blue action as both oxidant and antioxidant is rationalized based on similar previous cases. This mechanistic approach may have practical benefit. This review is important in conveying, for the first time, a unifying mechanism for toxicity based on electron transfer-reactive oxygen species-oxidative stress arising from imine-iminium.

show abstract

Section: Triphenylmethane Dyesmentioning

confidence: 99%

Section: Crystal Violet and Gentian Violetmentioning

confidence: 99%

Toxicity of imine–iminium dyes and pigments: electron transfer, radicals, oxidative stress and other physiological effects

Kovacic

Somanathan

2014

J of Applied Toxicology

View full text Add to dashboard Cite

show abstract

“…This structural stability lets CV persist in water bodies for prolonged periods, resulting in severe environmental contamination. Exposure to CV-contaminated water has been linked to various health issues in humans, including ocular toxicity, [6,7] cystitis, [8] skin irritation, [9] brain dysfunction, [10] and potential carcinogenic effects. [11][12][13][14][15] Removal of CV from wastewater is a challenging task.…”

mentioning

confidence: 99%

Waste‐Valorized Nanowebs for Crystal Violet Removal from Water

Maqbool,

Cavallini,

Lasemi

et al. 2024

Small Science

View full text Add to dashboard Cite

Lightweight, metal‐free, sustainable, and reusable adsorbent materials are of paramount significance in addressing the challenges of wastewater treatment. Accordingly, semi‐crystalline nanocellulose (NC) is extracted from tissue paper waste and used to modify polyacrylonitrile (PAN) to produce electrospun nanowebs with strand diameters from ≈180–300 nm. The incorporation of NC into PAN is confirmed by infrared and Raman spectroscopy and X‐Ray diffraction. When tested for crystal violet (CV) adsorption, NC‐modified PAN (20% NC@PAN) exhibits the highest CV removal capacity, achieving 91–94% removal over three cycles each, demonstrating exceptional recyclability. In contrast, unmodified PAN significantly decreases in CV adsorption capacity (from 59% to 48% in the third cycle), possibly due to an increased (≈36%) nanofiber diameter. The adsorption kinetics, exhibiting pseudo‐second order, interparticle (in between nanofibers) diffusion, and Elovich kinetic models emphasize the role of multilayer CV adsorption through reversible chemical interactions. Confocal micro‐Raman spectroscopy unveils a multifaceted CV adsorption mechanism, suggesting both surface and multilayer diffusion, with NC‐enhancing interactions. These findings demonstrate the potential of NC‐modified PAN nanowebs as effective and environmentally sustainable adsorbents for removing CV from aqueous solutions, suggesting promising practical applications.

show abstract

Exposure to Crystal Violet, Its Toxic, Genotoxic and Carcinogenic Effects on Environment and Its Degradation and Detoxification for Environmental Safety

Mani

Bharagava

2016

Reviews of Environmental Contamination and Toxicology

183

104

View full text Add to dashboard Cite

Crystal Violet (CV), a triphenylmethane dye, has been extensively used in human and veterinary medicine as a biological stain, as a textile dye in textile processing industries and also used to provide a deep violet color to paints and printing ink. CV is also used as a mutagenic and bacteriostatic agent in medical solutions and antimicrobial agent to prevent the fungal growth in poultry feed. Inspite of its many uses, CV has been reported as a recalcitrant dye molecule that persists in environment for a long period and pose toxic effects in environment. It acts as a mitotic poison, potent carcinogen and a potent clastogene promoting tumor growth in some species of fish. Thus, CV is regarded as a biohazard substance. Although, there are several physico-chemical methods such as adsorption, coagulation and ion-pair extraction reported for the removal of CV, but these methods are insufficient for the complete removal of CV from industrial wastewaters and also produce large quantity of sludge containing secondary pollutants. However, biological methods are regarded as cost-effective and eco-friendly for the treatment of industrial wastewaters, but these methods also have certain limitations. Therefore, there is an urgent need to develop such eco-friendly and cost-effective biological treatment methods, which can effectively remove the dye from industrial wastewaters for the safety of environment, as well as human and animal health.

show abstract

Chemical cystitis due to crystal violet dye: a case report

Cited by 6 publications

References 8 publications

Toxicity of imine–iminium dyes and pigments: electron transfer, radicals, oxidative stress and other physiological effects

Toxicity of imine–iminium dyes and pigments: electron transfer, radicals, oxidative stress and other physiological effects

Waste‐Valorized Nanowebs for Crystal Violet Removal from Water

Exposure to Crystal Violet, Its Toxic, Genotoxic and Carcinogenic Effects on Environment and Its Degradation and Detoxification for Environmental Safety

Contact Info

Product

Resources

About