Chemical Exposures: The Ugly Side of Beauty Products

Barrett, Julia R.

doi:10.1289/ehp.113-a24

Cited by 32 publications

(22 citation statements)

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“…These results suggest the possible contribution of unknown exposure pathways of such phthalates. A certain percentage of the Intake total ) Intake diet + Intake air (4) unassigned exposure pathways may be attributable to the use of personal care products to some extent because DMP, DEP, and DBP are known to be ingredients in personal care products (31) such as cosmetics, nail polishes, hair sprays, deodorants, and perfumes (31,32). It has not been confirmed whether phthalates in such products are actually transferred into the human blood stream; however, the following suggestive evidence has been reported.…”

Section: Resultsmentioning

confidence: 99%

Quantitative Identification of Unknown Exposure Pathways of Phthalates Based on Measuring Their Metabolites in Human Urine

Itoh

Yoshida

Masunaga

2007

Environ. Sci. Technol.

104

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Humans are exposed to ubiquitous phthalates via multiple pathways. Exposures to phthalates have been estimated in some previous risk assessments in Japan based on point-of-contact measurement or scenario evaluation approaches. While the Japanese national government has regulated the use of di(2-ethylhexyl)phthalate (DEHP) and excluded several other phthalates from its regulation based on some of them, it is unclear whether such past exposure assessment studies fully assessed total human exposure to phthalates. In the present study, we measured their urinary metabolites, which show direct evidence of human exposure to phthalates. We recruited voluntary participants (N = 36) who agreed to donate urine samples, and measured the urinary concentrations of phthalate metabolites using enzymatic deconjugation, solid-phase extraction, and high-performance liquid-chromatography isotope-dilution tandem mass spectrometry. We then derived the daily intakes of their respective phthalates based on steady state assumption and finally compared them with the corresponding estimated daily intakes of each phthalate via diet and air derived from previous exposure or risk assessments in Japan. These comparisons showed that exposures to dimethyl phthalate, diethyl phthalate, and di-n-butyl phthalate via diet and air accounted for less than half of their respective total exposures. On the other hand, it appears that dietary intake was more predictive for the total exposure to n-butyl-benzyl phthalate and DEHP. The probabilities that the log normal distribution of each phthalate daily intake estimated from the present study exceeds the corresponding tolerable daily intake were estimated to be less than 10(-4).

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Section: Resultsmentioning

confidence: 99%

Quantitative Identification of Unknown Exposure Pathways of Phthalates Based on Measuring Their Metabolites in Human Urine

Itoh

Yoshida

Masunaga

2007

Environ. Sci. Technol.

104

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“…They are also known as "smarsumer," a combination word of smart and consumer, who purchases the consumer goods after confirming the ingredients and raw materials of the product [10]. The emphasis of research about human safety of synthetic chemicals outweigh natural ingredients [11][12][13], while natural materials are still of toxicological concerns [14][15][16]. Through a simple Internet search or Mintel GNPD data [17], the number of ingredients in the cosmetics marketed is usually over 20.…”

Section: Introductionmentioning

confidence: 99%

Effect of Trust in Domain-Specific Information of Safety, Brand Loyalty, and Perceived Value for Cosmetics on Purchase Intentions in Mobile E-Commerce Context

Choi

Lee

2019

Sustainability

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In 2016, the safety issues of humidifier disinfectants and some other safety incidents in personal cares caused chemical phobia syndrome in the Korean society. This series of events has created a trend for cosmetic consumers to undermine brand confidence and to self-check the safety of commercial cosmetic formulations through mobile apps. The purpose of this study is to examine the influence of trust in domain specific information on the safety rating of cosmetic ingredients on the perceived value and the purchase intention of the cosmetics. The results of structural equation modeling showed that involvement of skin safety (ISS) had a positive effect on trust in domain specific information on safety (TDSI) and brand loyalty (BL). TDSI showed a positive effect on the perceived safety value (PFV) and the perceived social value (PSV), and BL had a positive effect on the PSV. ISS, TDSI, and PSV had a positive effect on the purchase intention (PI) of green-grade cosmetics (GGC). As hypothesized, BL had an adverse effect on PI of GGC. Given the results, utilizing the signal of the domain specific information may be recommended to new entrants to the cosmetic business or manufacturers with relatively weak brand power.

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“…Many hairdressers are lacking adequate knowledge on potential hazards of their occupation, as well as on preventive strategies for reducing them [15]. The main phthalates in cosmetics and personal care products are those of low molecular weight [16][17][18]. Phthalate…”

Section: Introductionmentioning

confidence: 99%

Phthalates Exposure and Occupational Symptoms among Slovakian Hairdressing Apprentices

et al. 2019

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The objectives of the study were to examine occupational exposure to phthalates of hairdressing apprentices from Slovakia (n = 74, 89.2% females; 10.8% males), outcomes related to body composition and pulmonary functions. We used high-performance liquid chromatography and tandem mass spectrometry to the quantified urinary concentration of phthalates. Pulmonary function test (PFT), anthropometric measurements, and questionnaire were also conducted. We observed a decrease of % of predicted values of forced vital capacity (FVC% of PV) related exposure to mono(2-ethyl-5-oxohexyl) phthalate (MEOHP; p = 0.054) and sum of bis(2-ethylhexyl) phthalate metabolites ( DEHP; p = 0.037), and a decrease of % of predicted values of vital capacity (VC% of PV) related to exposure to MEOHP, DEHP (p = 0.008), and mono(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP; p = 0.014) in females. We detected associations between forced vital capacity (FVC) with weight (p = 0.002) and fat-free mass index (FFMI, p = 0.010). Vital capacity (VC) and VC% of PV increased with weight, body mass index (BMI), waist circumference (WC), hip circumference (HC), waist-hip ratio (WHR), the waist-height ratio (WHtR), fat mass index (FMI) and FFMI in females (p ≤ 0.014). Results of multivariate regression between PFT and anthropometric parameters adjusted to phthalates indicated exposure to MnBP and MEHP, changing body structure (BMI and FMI), subsequently affecting values of FEV 1 /FVC. Appl. Sci. 2019, 9, 3321 2 of 15 esters were determined in five salons from the ten monitored in Taiwan by a walkthrough survey. Although concentrations of diester phthalates (dibutyl phthalate, diethyl phthalate, dimethyl phthalate, di[2-ethylhexyl] phthalate, and butyl benzyl phthalate) were below the occupational exposure limits, they were higher than what was found in general residential environments [19]. As a result, hairdressers are frequently occupationally exposed to phthalates contained in beauty products [20,21]. Health complications that affected various mucosal surfaces and oral and skin lesions, either independently or concurrently, have been significantly increased in the hairdressing apprentices [12,[22][23][24]. Dysfunction of pulmonary, immune, and other systems [10,[25][26][27] have been among various potential health impacts often ascribed to these exposures. The occupational environment of hairdressers has been found hazardous for the initiation of airway syndromes, varying from bronchial irritation to asthma [28] with a prevalence of 5%-25% [29][30][31]. Although most patients with occupational asthma are mature adults, there is evidence that the inflammation of airways started soon after early exposures in hairdressing apprenticeship [32,33]. Associations with other respiratory diseases and symptoms were also reported [12,[34][35][36][37][38][39][40]. Concerning outcomes of such exposures, as a possible mechanistic link to airway diseases, the modulatory effects on peroxisome proliferation activated receptors (PPAR) have been suggested [2].The aim of thi...

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Chemical Exposures: The Ugly Side of Beauty Products

Cited by 32 publications

References 0 publications

Quantitative Identification of Unknown Exposure Pathways of Phthalates Based on Measuring Their Metabolites in Human Urine

Quantitative Identification of Unknown Exposure Pathways of Phthalates Based on Measuring Their Metabolites in Human Urine

Effect of Trust in Domain-Specific Information of Safety, Brand Loyalty, and Perceived Value for Cosmetics on Purchase Intentions in Mobile E-Commerce Context

Phthalates Exposure and Occupational Symptoms among Slovakian Hairdressing Apprentices

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