“…Any patient-applied pretreatments can vary from patient to patient, and we do not want to change the epidermal kinetics. 9 Preoperatively, a complete and thorough history and physical examination are required. Evaluation of cardiac, hepatic, and renal function as well as any disorder that affects healing such as diabetes, collagen-vascular disease, history of radiation treatments, medications such as isotretinoin (Accutane, Roche, Nutley, New Jersey), and a history of herpes outbreaks should be well documented.…”