Chemical injuries of the oesophagus: aetiopathological issues in Nigeria

Thomas, Martins Oluwafemi; Ogunleye, Ezekiel O.; Somefun, Oladapo

doi:10.1186/1749-8090-4-56

Cited by 22 publications

(23 citation statements)

References 6 publications

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“…Many studies [1, 6, 13, 20] reported that ingestion of alkali is more prevalent than that of acid in corrosive oesophageal injuries. Thomas et al [9] however reported a contrary finding. Alkali is usually kept in containers without sealed covers by people that manufacture local soaps; accidental ingestion from mistaken identity was the mechanism of ingestion in all the children in this study.…”

Section: Discussionmentioning

confidence: 96%

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Corrosive oesophageal injuries: a preventable menace

Adedeji¹,

Tobih²,

Olaosun³

et al. 2013

Pan Afr Med J

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IntroductionPotentially catastrophic presentations and lifelong complications resulting from corrosive ingestions in humans is one of the most challenging situations encountered in clinical medical practice. This study reviewed pattern, mechanisms and associated socio-medical challenges with ingestion of corrosive agents as seen in a tertiary health institution in South-western Nigeria.MethodsA retrospective review of all patients that were managed for corrosive ingestion at Ladoke Akintola University of Technology Teaching Hospital, Osogbo, Osun State, Nigeria, over a seven year period.ResultsA total of 28 patients M:F: 1.6:1. There were 7 children and 21 adults. Majority (78.6%) of the patients ingested alkaline substances. Accidental ingestion occurred in 28.6% while 71.4% resulted from deliberate self harm especially among adults (66.7%). Almost two thirds (64.3%) of the patients presented after 48hrs of ingestion. Patients who presented early were managed conservatively. Most patients (64.3%) who presented late had nutritional and fluid rehabilitation. Two patients died from oesophageal perforation and resulting septicaemia. Psychiatric evaluation revealed that seven adults (25%) had psychotic illness while (42.9%) of the patients developed oesophageal strictures. Short segment strictures were managed with oesophageal dilatation with good outcome while long and multiple segment strictures were referred to cardiothoracic surgeons for management.ConclusionCorrosive oesophageal injuries remain a prevalent and preventable condition in the developing countries. Preventive strategies should include regulation and packaging of corrosive substances, organization of psychiatric services, and education of the population on corrosive ingestion.

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Section: Discussionmentioning

confidence: 96%

“…Caustic material ingestion is most frequently accidental in children particularly those from families with low income [7–9]. In adults, corrosives are usually ingested either for suicidal or for medicinal purposes [2, 7].…”

Section: Introductionmentioning

confidence: 99%

Corrosive oesophageal injuries: a preventable menace

Adedeji¹,

Tobih²,

Olaosun³

et al. 2013

Pan Afr Med J

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show abstract

“…Daha çok boş su ve meşrubat şişelerine doldurulan bu tür ürünler çocuklar tarafından içilebilir olarak algılanmaktadır. Özellikle de temizlik sırasında bu tür ürünlerin açıkta bırakılması içilme olasılığını daha da arttırmaktadır (8,25) . İçilen maddelere bakıldığında bu maddelerin ya meşrubat şişelerinde saklandığı ya da ebeveynler tarafından bardağa doldurulup kolay ulaşılabilir bir yerde unutulduğu görülmektedir.…”

Section: Discussionunclassified

Corosive ingestion in pediatric age group: Analysis of 681 patients

Aydın¹,

Özcan²,

Emre³

et al. 2012

TCCD

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“…Consequently, collagen deposition is minor until the second week after ingestion, and the healing process begins three weeks after ingestion. Three weeks after ingestion, tissue fibrosis occurs, resulting in narrowing of esophageal and/or stomach lumen and stricture formation (19). …”

Section: Corrosive Substancesmentioning

confidence: 99%

Corrosive Poisonings in Adults

Chibishev¹,

Pereska²,

Chibisheva³

et al. 2012

Mater Sociomed

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Ingestion of corrosive substances may cause severe to serious injuries of the upper gastrointestinal tract and the poisoning can even result in death. Acute corrosive intoxications pose a major problem in clinical toxicology since the most commonly affected population are the young with psychic disorders, suicidal intent and alcohol addiction. The golden standard for determination of the grade and extent of the lesion is esophagogastroduodenoscopy performed in the first 12-24 hours following corrosive ingestion. The most common late complications are esophageal stenosis, gastric stenosis of the antrum and pyloris, and rarely carcinoma of the upper gastrointestinal tract. Treatment of the acute corrosive intoxications include: neutralization of corrosive agents, antibiotics, anti-secretory therapy, nutritional support, collagen synthesis inhibitors, esophageal dilation and stent placement, and surgery.

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Chemical injuries of the oesophagus: aetiopathological issues in Nigeria

Abstract: Background: Chemical injuries of the oesophagus occur worldwide. There is paucity of information on aetiopathological profile of chemical injuries of the oesophagus in Nigeria.

Cited by 22 publications

References 6 publications

Corrosive oesophageal injuries: a preventable menace

Corrosive oesophageal injuries: a preventable menace

Corosive ingestion in pediatric age group: Analysis of 681 patients

Corrosive Poisonings in Adults

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