Chemical injury of arteries

A Fine Structure Study of Injury to the Endothelial Cells of the Rabbit Abdominal Aorta by Various Stimuli

“…The most extensive damage of the endothelial lining was found after perfusions with hypertonic glucose, with cell necrosis similar to the observations of Williams and Montgomery (61). The increase in permeability of the internal elastic membrane to metal ions suggests that the probable removal of water from the matrix of elastin and mucopolysaccharide has altered its structure so drastically that it loses its usual barrier characteristics.…”

“…Numerous studies have also been made on the changes to the arterial wall following injury by physical or chemical agents, usually concurrently with hypercholesterolemia (1, 10,11,14,23,24,26,48,52,56,57,60,61 ) . We have felt that a description of the ultra-structural changes to the aortic endothelial lining caused by a wide variety of irritations would be of interest, since no such study using the electron microscope has been reported in the literature.…”

Unusual Presentation of Axillary Artery Injury

“…Drug addicted patients tend to have fibrotic thrombosed peripheral veins due to repetitive injections of highly irritating drugs [4]. We have seen many drug addicted patients with compromised superficial peripheral venous system in both upper and lower limbs in which obtaining a peripheral line is too challenging and hence can lead to accidental intraarterial injection of drugs.…”