Chemical ionization mass spectrometry

Munson, Burnaby

doi:10.1021/ac60307a042

Cited by 67 publications

(12 citation statements)

References 23 publications

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“…That is, the resulting CI mass spectra produce ions characteristic of the EI mass spectra with decreasing proton affinity of the reagent gas. 12 A similar pattern was exhibited by CI mass spectra of M-4365 A2 (2) as indicated in Table 1, except for the de-epoxidation process ( m / z 582+ m / z 566).…”

Section: Chemical Ionization Mass Spectra Of M-4365 Gz and A2supporting

confidence: 74%

Chemical ionization mass spectrometry of macrolide antibiotics. III—M-4365 and related compounds

Suzuki

Harada

Takeda

et al. 1981

Biol. Mass Spectrom.

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Chemical ionization mass spectra of several 16-membered basic macrolide antibiotics containing an amino sugar are described. Depending on the reagent gas used (methane, isobutane or ammonia), a common pattern is exhibited by the chemical ionization mass spectra of all the compounds. That is, they show the protonated molecular ion as the base peak, which clearly indicates the molecular weight. Fragmentation involving carbon-carbon bond fission rarely occurs. As the major fragmentation pathway, the glycosidic bond is cleaved at both sides of the glycosidic oxygen atom to produce two aglycone-ions and three sugar-derived ions. These are shown to be useful in the structural characterization of new macrolide antibiotics.

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Section: Chemical Ionization Mass Spectra Of M-4365 Gz and A2supporting

confidence: 74%

Chemical ionization mass spectrometry of macrolide antibiotics. III—M-4365 and related compounds

Suzuki

Harada

Takeda

et al. 1981

Biol. Mass Spectrom.

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“…The use of ionization techniques causing negligible fragmentation such as field ionization (19), chemical ionization . (20), or low-voltage electron-impact ionization (21) seems to be the obvious experimental approach to this problem. Apart from the earlier mentioned experiments with high resolution field ionization mass spectrometry ( I @ , we are at present engaged in low-voltage electron-impact ionization studies, which also encompass higher mass ranges than the study reported here (22).…”

Section: Resultsmentioning

confidence: 99%

Technique for fast and reproducible fingerprinting of bacteria by pyrolysis mass spectrometry

Meuzelaar¹,

Kistemaker²

1973

Anal. Chem.

153

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“…The chemical ionization mass spectra of sample molecules are typically simple and they often consist of the molecular ion (M+ or MH2+ with little concomitant fragmentation. Therefore, chemical ionization mass spectrometry has enjoyed considerable application in the areas of quantitative and qualitative analysis (51)(52)(53).…”

Section: Gas Chromatography Of Metal Complexesmentioning

confidence: 99%

Use of Negative Chemical Ionization Mass Spectrometry for the Trace Analysis of Metals

Risby¹

1980

Environmental Health Perspectives

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The synthesis of various volatile and thermally stable derivatives of metals ions has permitted the use of conventional mass spectrometry for trace metal analysis. This paper reviews the development of the field using electron impact and chemical ionization mass spectrometry. This latter methodology produces simple mass spectra that enable complex mixtures to be analyzed. In addition the use of negative ion detection has produced selective ionization since many metal chelates contain heteroatoms which are electronegative.A discussion of the use of this general methodology for trace metal analysis is included, together with its applications to the analysis of ruthenium in automobile exhaust emissions and iron in red blood cells from laboratory rats. The future use of this methodology is expected to be for the monitoring of stable metal isotopes. This procedure could be used to follow these tracers in clinical and environmental studies and it is expected that their use will replace radioactive isotopes in most studies.

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Chemical ionization mass spectrometry

Abstract: Del. 19711 /'"'hemical ionization (Cl) mass ^spectrometry is a relatively new technique for the production of mass spectra of compounds in which the ions from the molecules of interest are formed by ion-molecule reactions. The method of ion pro-

Cited by 67 publications

References 23 publications

Chemical ionization mass spectrometry of macrolide antibiotics. III—M-4365 and related compounds

Chemical ionization mass spectrometry of macrolide antibiotics. III—M-4365 and related compounds

Technique for fast and reproducible fingerprinting of bacteria by pyrolysis mass spectrometry

Use of Negative Chemical Ionization Mass Spectrometry for the Trace Analysis of Metals

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