Chemical modification of the alkaloid 2,3-tetramethylene-3,4-dihydroquinazol-4-one

11-(2-Oxopyrrolidin-1-ylmethyl)-1,2,3,4,5,6,11,11a-octahydropyrido[2,1-b]quinazolin-6-one dihydrate

“…Alkaloid pyrido-quinazoline derivatives are widespread compounds in plants (Fitzgerald et al, 1966), was elaborated simple and convenient method of synthesis (Shakhidoyatov 1983;Barakat 1998), was studied structure and modification of pyrido-quinazoline derivatives (Tashkhodzhaev et al, 1995;Turgunov et al, 2003;Shakhidoyatov et al, 2007;Tozhiboev et al, 2007).…”

“…Alkaloid pyrido-quinazoline derivatives are widespread compounds in plants (Fitzgerald et al, 1966), was elaborated simple and convenient method of synthesis (Shakhidoyatov 1983;Barakat 1998), was studied structure and modification of pyrido-quinazoline derivatives (Tashkhodzhaev et al, 1995;Turgunov et al, 2003;Shakhidoyatov et al, 2007;Tozhiboev et al, 2007). Amidomethylation (Pandey et al, 2008;Ibragimov et al, 2004) of 1,2-dihydro derivatives tricyclic quinazolin-4-ones allows to enter in molecule alkyl group and to get the series of the new compounds.…”