Chemical profile, mosquitocidal, and biochemical effects of essential oil and major components of Dysphania ambrosioides against Culex quinquefasciatus Say

Almadiy, Abdulrhman A.

doi:10.1007/s11356-020-10137-z

Cited by 10 publications

(2 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The aqueous extract of O. tenuiflorum analyzed in this study showed significant peaks of trans-β-ocimene, 6-methyl-2-methylene-6-(4-methyl-3-pentenyl)-bicyclo[3.1.1]heptane, 1-(1,5-dimethyl-4-hexenyl)-4-methylbenzene, 5-(1,5-dimethyl-4-hexenyl)-2-methyl-1,3-cyclohexadiene, cis-α-bisabolene, 3,7-dimethyl-1,3,6-octatriene, pcymene, α-farnesene, hexadecyl-oxirane, octadecanoic acid, and cis,cis,cis-7,10,13-hexadecatrienal. Prior studies have documented the larvicidal, insecticidal, and pesticidal effects of these bioactive compounds [25][26][27][28][29][31][32][33][34]. In the same way, the aqueous extracts contained significant amounts of o-cymene, 1,3,5-trimethyl-cyclohexane, 4-methoxy-benzaldehyde, and α-methyl-benzenemethanol.…”

Section: Plos Onementioning

confidence: 87%

Phytomediated stress modulates antioxidant status, induces overexpression of CYP6M2, Hsp70, α-esterase, and suppresses the ABC transporter in Anopheles gambiae (sensu stricto) exposed to Ocimum tenuiflorum extracts

Aremu,

Dare,

Adekale

et al. 2024

PLoS ONE

View full text Add to dashboard Cite

The incorporation of phytoactive compounds in the management of malarial vectors holds promise for the development of innovative and efficient alternatives. Nevertheless, the molecular and physiological responses that these bioactive substances induce remain underexplored. This present study investigated the toxicity of different concentrations of aqueous and methanol extracts of Ocimum tenuiflorum against larvae of Anopheles gambiae (sensu stricto) and unraveled the possible underlying molecular pathways responsible for the observed physiological effects. FTIR and GCMS analyses of phytoactive compounds in aqueous and methanol crude extracts of O. tenuiflorum showed the presence of OH stretching vibration, C = C stretching modes of aromatics and methylene rocking vibration; ring deformation mode with high levels of trans-β-ocimene, 3,7-dimethyl-1,3,6-octatriene in aqueous extract and 4-methoxy-benzaldehyde, 1,3,5-trimethyl-cyclohexane and o-cymene in methanol extract. The percentage mortality upon exposure to methanol and aqueous extracts of O. tenuiflorum were 21.1% and 26.1% at 24 h, 27.8% and 36.1% at 48 h and 36.1% and 45% at 72 h respectively. Using reverse transcription quantitative polymerase chain reaction (RT-qPCR), down-regulation of ABC transporter, overexpression of CYP6M2, Hsp70, and α-esterase, coupled with significantly increased levels of SOD, CAT, and GSH, were observed in An. gambiae (s.s.) exposed to aqueous and methanol extracts of O. tenuiflorum as compared to the control. Findings from this study have significant implications for our understanding of how An. gambiae (s.s.) larvae detoxify phytoactive compounds.

show abstract

Section: Plos Onementioning

confidence: 87%

Phytomediated stress modulates antioxidant status, induces overexpression of CYP6M2, Hsp70, α-esterase, and suppresses the ABC transporter in Anopheles gambiae (sensu stricto) exposed to Ocimum tenuiflorum extracts

Aremu,

Dare,

Adekale

et al. 2024

PLoS ONE

View full text Add to dashboard Cite

show abstract

“…D. ambrosioides exhibits high antimicrobial and antioxidant activities and can enhance the antibacterial activity with the synergistic effect of antibiotics. At the same time, some compounds contained in it can achieve the purpose of killing mosquitoes by destroying the nervous system of insects and inhibiting the activity of key enzymes [17][18][19].…”

Section: Introductionmentioning

confidence: 99%

Comparative Analysis of Six Chloroplast Genomes in Chenopodium and Its Related Genera (Amaranthaceae): New Insights into Phylogenetic Relationships and the Development of Species-Specific Molecular Markers

Wei,

Chen,

Ding

et al. 2023

Genes

View full text Add to dashboard Cite

Species within the genus Chenopodium hold significant research interest due to their nutritional richness and salt tolerance. However, the morphological similarities among closely related species and a dearth of genomic resources have impeded their comprehensive study and utilization. In the present research, we conduct the sequencing and assembly of chloroplast (cp) genomes from six Chenopodium and related species, five of which were sequenced for the first time. These genomes ranged in length from 151,850 to 152,215 base pairs, showcased typical quadripartite structures, and encoded 85 protein-coding genes (PCGs), 1 pseudogene, 37 tRNA genes, and 8 rRNA genes. Compared with the previously published sequences of related species, these cp genomes are relatively conservative, but there are also some interspecific differences, such as inversion and IR region contraction. We discerned 929 simple sequence repeats (SSRs) and a series of highly variable regions across 16 related species, predominantly situated in the intergenic spacer (IGS) region and introns. The phylogenetic evaluations revealed that Chenopodium is more closely related to genera such as Atriplex, Beta, Dysphania, and Oxybase than to other members of the Amaranthaceae family. These lineages shared a common ancestor approximately 60.80 million years ago, after which they diverged into distinct genera. Based on InDels and SNPs between species, we designed 12 pairs of primers for species identification, and experiments confirmed that they could completely distinguish 10 related species.

show abstract

Dysphania ambrosioides essential oils: from pharmacological agents to uses in modern crop protection—a review

Singh

Pandey

2021

Phytochem Rev

View full text Add to dashboard Cite

Chemical profile, mosquitocidal, and biochemical effects of essential oil and major components of Dysphania ambrosioides against Culex quinquefasciatus Say

Cited by 10 publications

References 27 publications

Phytomediated stress modulates antioxidant status, induces overexpression of CYP6M2, Hsp70, α-esterase, and suppresses the ABC transporter in Anopheles gambiae (sensu stricto) exposed to Ocimum tenuiflorum extracts

Phytomediated stress modulates antioxidant status, induces overexpression of CYP6M2, Hsp70, α-esterase, and suppresses the ABC transporter in Anopheles gambiae (sensu stricto) exposed to Ocimum tenuiflorum extracts

Comparative Analysis of Six Chloroplast Genomes in Chenopodium and Its Related Genera (Amaranthaceae): New Insights into Phylogenetic Relationships and the Development of Species-Specific Molecular Markers

Dysphania ambrosioides essential oils: from pharmacological agents to uses in modern crop protection—a review

Contact Info

Product

Resources

About